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(10)
By Target- PROTAC Linker
- ADC Linker(3)
- Drug-Linker Conjugates for ADC(3)
- Apoptosis(1)
- Autophagy(1)
- JAK(1)
- Mitophagy(1)
- Tyrosine Kinases(1)
- Others(3)
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By Target By ResearchField- Cancer(11)
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Results for "
T1829
" in TargetMol Product Catalog- Inhibitors & Agonists11
- PROTAC Products10
- ADC/ADC Related6
Ruxolitinib
Cited
INCB018424, (R)-Ruxolitinib
T1829941678-49-5
Ruxolitinib (INCB018424) is a JAK1/2 inhibitor (IC50=3.3/2.8 nM) that is potent and selective. Rixolitinib exhibits antitumor activity and induces autophagy and apoptosis.
- $53
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QTY
CitedMal-PEG5-Boc
Mal-PEG5-T-Butyl Ester, Mal-PEG5-COOtBu
T182952250216-91-0
Mal-PEG5-Boc (Mal-PEG5-COOtBu) is a PEG-based PROTAC linker. Mal-PEG5-Boc can be used in the synthesis of PROTACs.
- $30
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QTY
Mal-PEG4-VA
T182901800456-31-8
Mal-PEG4-VA, a noncleavable ADC linker featuring a Maleimide group, is utilized in the synthesis of antibody-drug conjugates.
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Mal-PEG4-Val-Cit-PAB
T182911949793-41-2
Mal-PEG4-Val-Cit-PAB, a cleavable ADC linker incorporating a Maleimide moiety, finds application in the construction of antibody-drug conjugates (ADCs)[1].
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Mal-PEG4-VC-PAB-DMEA-PNU-159682
T182922259318-52-8
Mal-PEG4-VC-PAB-DMEA-PNU-159682 is a drug-linker conjugate designed for antibody-drug conjugate (ADC) therapy. It combines the ADC linker, Mal-PEG4-VC-PAB, with the potent ADC cytotoxin, DMEA-PNU-159682. The cytotoxin, DMEA-PNU-159682, is derived from metabolites of nemorubicin (MMDX) found in liver microsomes, as well as the ADC cytotoxin PNU-159682 [1].
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Mal-PEG4-VC-PAB-DMEA-Seco-Duocarmycin SA
T182932259318-49-3
Mal-PEG4-VC-PAB-DMEA-Seco-Duocarmycin SA is an antibody-drug conjugate linker, integrating the antitumor antibiotic Duocarmycin SA via the Mal-PEG4-VC-PAB-DMEA-Seco linker, aimed at targeted cancer therapy.
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Mal-PEG4-VC-PAB-DMEA
T182941569261-93-3
Mal-PEG4-VC-PAB-DMEA, a cleavable ADC linker incorporating a Maleimide moiety, is employed in the synthesis of antibody-drug conjugates (ADCs)[1].
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Mal-PEG5-mal
T18296113387-03-4
Mal-PEG5-mal is a PEG-based linker for PROTACs, joining two essential ligands crucial for PROTAC molecule formation and enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
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Mal-PEG6-mal
T18297
Mal-PEG6-mal is a PEG-based linker for PROTACs, joining two essential ligands crucial for forming PROTAC molecules. It enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
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Mal-PEG8-alcohol
T182982353409-63-7
Mal-PEG8-alcohol is a PEG-based linker used in PROTACs, joining two essential ligands crucial for forming PROTAC molecules, and enabling selective protein degradation via the ubiquitin-proteasome system within cells.
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Mal-PEG8-Val-Cit-PAB-MMAE
T182992353409-69-3
Mal-PEG8-Val-Cit-PAB-MMAE is a cleavable 8-unit PEG ADC linker utilized in the synthesis of antibody-drug conjugates (ADCs)[1].
- $195
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