15
2
3
1
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T4213 | NCT-503 | NCT 503 | Dehydrogenase , FLT , TAM Receptor |
NCT-503 is an inhibitor of 3-phosphoglycerate dehydrogenase (PHGDH), inhibiting serine synthesis from 3-phosphoglycerate in cells. | |||
T9996 | NCT-58 | NCT58 | HSP |
NCT-58 is a potent C-terminal HSP90 inhibitor. NCT-58 does not induce the heat shock response (HSR). NCT-58 elicits anti-tumor activity via the simultaneous downregulation of HER family members as well as inhibition of ... | |||
T38605 | NCT-504 | Others | |
NCT-504, a selective allosteric inhibitor of PIP4Kγ, exhibits an IC50 value of 15.8 μM. It holds promise for the investigation of Huntington's disease. | |||
T12196 | NCT-505 | Dehydrogenase | |
NCT-505 is a potent and selective inhibitor of aldehyde dehydrogenase (ALDH1A1, IC50 = 7 nM) and a weak inhibitor of hALDH1A2, hALDH1A3, hALDH2, hALDH3A1 with IC50 values of >57 μM, 22.8 μM, 20.1 μM, >57 μM respectively... | |||
T6903 | NCT-501 | NCT501 | Dehydrogenase |
NCT-501 is a potent and selective inhibitor of Aldehyde Dehydrogenase 1A1 (ALDH1A1) with IC50 of 40 nM. | |||
T16277 | NCT-502 | N-(4,6-dimethylpyridin-2-yl)-4-[5-(trifluoromethyl)pyridin-2-yl]piperazine-1-carbothioamide | Dehydrogenase |
NCT-502 (N-(4,6-dimethylpyridin-2-yl)-4-[5-(trifluoromethyl)pyridin-2-yl]piperazine-1-carbothioamide) is a human phosphoglycerate dehydrogenase inhibitor, cytotoxic to PHGDH-dependent cancer cells. It decreases glucose-d... | |||
T25858 | NCT-10b | NCT 10b | |
NCT-10b is a selective inhibitor of HDAC6. | |||
T41159 | NCT 501 hydrochloride | ||
NCT 501 hydrochloride is a potent and selective ALDH1A1 inhibitor (IC50 = 40 nM). Exhibits >1000-fold selectivity for ALDH1A1 over ALDH3A1, ALDH1B1, ALDH2, HPGD and HSD17β4. Also selective over a panel of 168 GPCRs. Bloo... | |||
T39485 | NCT-501 hydrochloride | ||
NCT-501 hydrochloride is a highly potent and selective inhibitor of aldehyde dehydrogenase 1A1 (ALDH1A1), which is based on theophylline. It effectively inhibits hALDH1A1 with an IC50 value of 40 nM, exhibiting superior ... | |||
T12197 | NCT-506 | Others | |
NCT-506 is an orally bioavailable inhibitors of aldehyde dehydrogenase 1A1 (ALDH1A1) (IC50 of 7 nM). | |||
T75344 | NCT-TFP | ||
NCT-TFP is PARP probe used to identifying Poly(ADP-ribose) polymerases (PARP) inhibitors[1]. | |||
T23150 | PHGDH-inactive | Others | |
inactive analog of the 3-phosphoglycerate dehydrogenase (PHGDH) inhibitors NCT-502 and NCT-503 | |||
T60030 | NCT02 | ||
NCT02, a cyclin K degrader, promotes the ubiquitination and proteasomal degradation of cyclin K (CCNK) and its complex partner CDK12, showing promise for metastatic colorectal cancer (CRC) research[1]. | |||
T80371 | Distinctin | ||
Distinctin, an antimicrobial peptide derived from frog skin, exhibits antibacterial activity against a range of pathogens including E. faecalis, P. aeruginosa, S. aureus, and E. coli, with minimum inhibitory concentratio... | |||
T34193 | Punctaporonin D | M 167906,M167906 | |
Punctaporonin D is an isomeric allylic alcohol from the fungus Poronia punctata. |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T26167 | Rubropunctatin | Rubropunctamine | |
Rubropunctatin is a monascus pigment with very potent cancer cell proliferation inhibitory effects. | |||
TN3290 | 8-O-Demethyl-7-O-methyl-3,9-dihydropunctatin | Others | |
8-O-Demethyl-7-O-methyl-3,9-dihydropunctatin is a natural product for research related to life sciences. The catalog number is TN3290 and the CAS number is 93078-83-2. |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-02910 | Nicastrin Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Nicastrin Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 73 kDa and the accession number is P57716. | |||
TMPY-03074 | Nicastrin Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 Cells |
Nicastrin Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 98.5 kDa and the accession number is P57716. | |||
TMPH-03528 | Chemotaxis inhibitory Protein, S. aureus (strain NCTC 8325/PS47), Recombinant (His & Myc) | Staphylococcus aureus | E. coli |
Involved in countering the first line of host defense mechanisms. Specifically inhibits the response of human neutrophils and monocytes to complement anaphylatoxin C5a and formylated peptides, like N-formyl-methionyl-leu... |
Cat No. | Product Name | ||
---|---|---|---|
L7810 | High Solubility Polyfunctional Group Fragment Library | 1159 compounds | |
Highly soluble multifunctional fragment library contains 1159 kinds of fragment molecules. |