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Search Results for " nct "

Targets

15

Compounds

2

Natural Products

3

Recombinant Proteins

1

Libraries

Cat No. Product Name Synonyms Targets
T4213 NCT-503 NCT 503 Dehydrogenase , FLT , TAM Receptor
NCT-503 is an inhibitor of 3-phosphoglycerate dehydrogenase (PHGDH), inhibiting serine synthesis from 3-phosphoglycerate in cells.
T9996 NCT-58 NCT58 HSP
NCT-58 is a potent C-terminal HSP90 inhibitor. NCT-58 does not induce the heat shock response (HSR). NCT-58 elicits anti-tumor activity via the simultaneous downregulation of HER family members as well as inhibition of ...
T38605 NCT-504 Others
NCT-504, a selective allosteric inhibitor of PIP4Kγ, exhibits an IC50 value of 15.8 μM. It holds promise for the investigation of Huntington's disease.
T12196 NCT-505 Dehydrogenase
NCT-505 is a potent and selective inhibitor of aldehyde dehydrogenase (ALDH1A1, IC50 = 7 nM) and a weak inhibitor of hALDH1A2, hALDH1A3, hALDH2, hALDH3A1 with IC50 values of >57 μM, 22.8 μM, 20.1 μM, >57 μM respectively...
T6903 NCT-501 NCT501 Dehydrogenase
NCT-501 is a potent and selective inhibitor of Aldehyde Dehydrogenase 1A1 (ALDH1A1) with IC50 of 40 nM.
T16277 NCT-502 N-(4,6-dimethylpyridin-2-yl)-4-[5-(trifluoromethyl)pyridin-2-yl]piperazine-1-carbothioamide Dehydrogenase
NCT-502 (N-(4,6-dimethylpyridin-2-yl)-4-[5-(trifluoromethyl)pyridin-2-yl]piperazine-1-carbothioamide) is a human phosphoglycerate dehydrogenase inhibitor, cytotoxic to PHGDH-dependent cancer cells. It decreases glucose-d...
T25858 NCT-10b NCT 10b
NCT-10b is a selective inhibitor of HDAC6.
T41159 NCT 501 hydrochloride
NCT 501 hydrochloride is a potent and selective ALDH1A1 inhibitor (IC50 = 40 nM). Exhibits >1000-fold selectivity for ALDH1A1 over ALDH3A1, ALDH1B1, ALDH2, HPGD and HSD17β4. Also selective over a panel of 168 GPCRs. Bloo...
T39485 NCT-501 hydrochloride
NCT-501 hydrochloride is a highly potent and selective inhibitor of aldehyde dehydrogenase 1A1 (ALDH1A1), which is based on theophylline. It effectively inhibits hALDH1A1 with an IC50 value of 40 nM, exhibiting superior ...
T12197 NCT-506 Others
NCT-506 is an orally bioavailable inhibitors of aldehyde dehydrogenase 1A1 (ALDH1A1) (IC50 of 7 nM).
T75344 NCT-TFP
NCT-TFP is PARP probe used to identifying Poly(ADP-ribose) polymerases (PARP) inhibitors[1].
T23150 PHGDH-inactive Others
inactive analog of the 3-phosphoglycerate dehydrogenase (PHGDH) inhibitors NCT-502 and NCT-503
T60030 NCT02
NCT02, a cyclin K degrader, promotes the ubiquitination and proteasomal degradation of cyclin K (CCNK) and its complex partner CDK12, showing promise for metastatic colorectal cancer (CRC) research[1].
T80371 Distinctin
Distinctin, an antimicrobial peptide derived from frog skin, exhibits antibacterial activity against a range of pathogens including E. faecalis, P. aeruginosa, S. aureus, and E. coli, with minimum inhibitory concentratio...
T34193 Punctaporonin D M 167906,M167906
Punctaporonin D is an isomeric allylic alcohol from the fungus Poronia punctata.
Cat No. Product Name Synonyms Targets
T26167 Rubropunctatin Rubropunctamine
Rubropunctatin is a monascus pigment with very potent cancer cell proliferation inhibitory effects.
TN3290 8-O-Demethyl-7-O-methyl-3,9-dihydropunctatin Others
8-O-Demethyl-7-O-methyl-3,9-dihydropunctatin is a natural product for research related to life sciences. The catalog number is TN3290 and the CAS number is 93078-83-2.

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-02910 Nicastrin Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
Nicastrin Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 73 kDa and the accession number is P57716.
TMPY-03074 Nicastrin Protein, Mouse, Recombinant (hFc) Mouse HEK293 Cells
Nicastrin Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 98.5 kDa and the accession number is P57716.
TMPH-03528 Chemotaxis inhibitory Protein, S. aureus (strain NCTC 8325/PS47), Recombinant (His & Myc) Staphylococcus aureus E. coli
Involved in countering the first line of host defense mechanisms. Specifically inhibits the response of human neutrophils and monocytes to complement anaphylatoxin C5a and formylated peptides, like N-formyl-methionyl-leu...
Cat No. Product Name
L7810 High Solubility Polyfunctional Group Fragment Library

1159 compounds
Highly soluble multifunctional fragment library contains 1159 kinds of fragment molecules.
TargetMol