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(3)
By Target- MLK
- VEGFR(2)
- Aurora Kinase(1)
- Autophagy(1)
- Bcr-Abl(1)
- CDK(1)
- DNA Alkylation(1)
- IGF-1R(1)
- LRRK2(1)
- MEK(1)
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Results for "
MLKs
" in TargetMol Product Catalog- Inhibitors & Agonists3
URMC-099
T60571229582-33-5
URMC-099 is an orally bioavailable, brain penetrant MLK inhibitor (IC50: 19/42/14/150 nM, for MLK1/MLK2/MLK3/DLK), and also inhibits LRRK2 activity (IC50: 11 nM).
ROCKMLKVEGFRSGKDNA AlkylationTrk receptorc-Met/HGFRLRRK2MEKIGF-1RSykBcr-AblCDKSrcAurora KinaseAutophagy
- $52
Size
QTY
Necrosulfonamide
(E)-Necrosulfonamide
T69041360614-48-7
Necrosulfonamide ((E)-Necrosulfonamide) is a necroptosis inhibitor that targets MLKL and is selective. Necrosulfonamide prevents the MLKL-RIP1-RIP3 necrosomal complex from interacting with its downstream effectors.
- $52
Size
QTY
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