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(1)
By Target- AIM2
- Caspase(1)
- Dehydrogenase(1)
- IL Receptor(1)
- NOD-like Receptor (NLR)(1)
- ROS(1)
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Results for "
JC2-11
" in TargetMol Product Catalog- Inhibitors & Agonists1
JC2-11
T77579937820-89-8
JC2-11 is an inhibitory compound for inflammation.JC2-11 inhibits the recruitment domain-containing proteins NLRC 4, atypical in melanoma 2 (AIM 2) and atypical (NC) inflammatory vesicles by disrupting reactive oxygen species (ROS) production and caspase-1 activity.JC2-11 reduces caspase-1 (p20) secretion, gasdermin D (GSDMD) cleavage, IL-1β and lactate dehydrogenase (LDH) activity in inflammatory vesicles. JC2-11 reduced caspase-1 (p20) secretion, gasdermin D (GSDMD) cleavage, IL-1β and lactate dehydrogenase (LDH) release from inflammatory vesicles.
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