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Search Results for " hbt-o "

1

Compounds

50

Recombinant Proteins

Cat No. Product Name
T32047 HBT-O
HBT-O is a fluorescent probe used to monitor subtle pH fluctuations in living cells.
Cat No. Product Name Species Source
TMPY-05822 Hepatitis B Virus (HBV)(ayw/France/Tiollais/1979) Capsid protein (His) HBV E. coli
Hepatitis B virus (HBV) capsid assembly is a critical step in the propagation of the virus and is mediated by the core protein. The first cytoplasmic step in the formation of an infectious HBV virion is the formation of a capsid containing pregenomic RNA (pgRNA) and the viral polymerase (Pol). HBV capsid assembly is an attractive target for new antiviral therapies.
TMPY-00672 Azurocidin/CAP37 Protein, Human, Recombinant (His) Human HEK293
Azurocidin (AZU1), also known as heparin-binding protein (HBP) or cationic antimicrobial protein 37 (CAP37), is an azurophil granule antibiotic protein, with monocyte chemotactic and antibacterial activity. The Azurophil granules, specialized lysosomes of the neutrophil, contain at least 10 proteins implicated in the killing of microorganisms. Azurocidin is a member of the serine protease family that includes Cathepsin G, neutrophil elastase (NE), and proteinase 3 (PR3), however, Azurocidin is n...
TMPY-01912 Cadherin 17/CDH17 Protein, Human, Recombinant (His) Human HEK293
Cadherin-17 or LI-cadherin is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. Cadherin-17/LI-cadherin is a cadherin-like protein consisting of an extracellular region, 7 cadherin domains, and a transmembrane region but lacking the conserved cytoplasmic domain. The protein is a component of the gastrointestinal tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step in oral absorption of ...
TMPY-01935 C-Kit Protein, Human, Recombinant (His) Human HEK293
C-Kit is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). c-Kit contains 5 Ig-like C2-type (immunoglobulin-like) domains and 1 protein kinase domain. It belongs to the protein kinase superfamily, tyr protein kinase family, and CSF-1/PDGF receptor subfamily. C-Kit has tyrosine-protein kinase activity. Binding of the ligands leads to the autophosphorylation of KIT and its association with substrates such as phosphatidylinositol 3-kinase. Antibodies...
TMPY-04051 C-Kit Protein, Human, Recombinant (hFc) Human HEK293
C-Kit is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). c-Kit contains 5 Ig-like C2-type (immunoglobulin-like) domains and 1 protein kinase domain. It belongs to the protein kinase superfamily, tyr protein kinase family, and CSF-1/PDGF receptor subfamily. C-Kit has tyrosine-protein kinase activity. Binding of the ligands leads to the autophosphorylation of KIT and its association with substrates such as phosphatidylinositol 3-kinase. Antibodies...
TMPY-01168 ALK-1 Protein, Human, Recombinant (His) Human HEK293
Activin A receptor, type II-like 1 (ACVRL1), also known as ALK-1 (activin receptor-like kinase 1), is an endothelial-specific type I receptor of the TGF-beta (transforming growth factor beta) receptor family of ligands. On ligand binding, a heteromeric receptor complex forms consisting of two type II and two type I transmembrane serine/threonine kinases. ACVRL1 protein is expressed in certain blood vessels of kidney, spleen, heart and intestine, serving as an important role during vascular devel...
TMPY-05004 FGF4 Protein, Human, Recombinant Human E. coli
FGF (fibroblast growth factor) signalling is known to be required for many aspects of mesoderm formation and patterning during Xenopus development and has been implicated in regulating genes required for the specification of both blood and skeletal muscle lineages. Fibroblast growth factor 4 (FGF4) signaling induces differentiation from embryonic stem cells (ESCs) via the phosphorylation of downstream molecules such as mitogen-activated protein kinase/extracellular signal-related kinase (MEK) a...
TMPY-02835 Beta Defensin 3/DEFB103A Protein, Human, Recombinant (His) Human E. coli
Beta-defensin 3 is a member of the defensin family. Defensin family is comprised by microbicidal and cytotoxic peptides made by neutrophils. Members of the beta-defensin 3 family are highly similar in protein sequence. Beta-defensin 3 shows antimicrobial activity against Gram-positive bacteria S.aureus and S.pyogenes, Gram-negative bacteria P.aeruginosa and E.coli and the yeast C.albicans. Beta-defensin 3 is abundantly expressed in skin and tonsils, and to a lesser extent in trachea, uterus, kid...
TMPK-00777 CD117 Protein, Mouse, Recombinant (His) Mouse HEK293
The c-kit proto-oncogen (CD 117) has been shown to be present in several cell types including normal and neoplastic hemopoietic cells. Among normal BM cells, CD117 expression has been found in about half of the CD34 precursors including progenitors committed to the erythroid, granulo-monocytic, and megakaryocytic cell lineages.
TMPK-01270 CD117 Protein, Cynomolgus/Rhesus macaque, Recombinant (His) Cynomolgus,Rhesus macaque HEK293
The c-kit proto-oncogen (CD117) has been shown to be present in several cell types including normal and neoplastic hemopoietic cells. Among normal BM cells, CD117 expression has been found in about half of the CD34 precursors including progenitors committed to the erythroid, granulo-monocytic, and megakaryocytic cell lineages.
TMPJ-01296 SULT4A1 Protein, Human, Recombinant Human E. coli
Sulfotransferase 4A1 (ST4A1) is a member of the Sulfotransferase 1 family. ST4A1 is highly expressed in the cerebral cortex and frontal lobe, but no expression is detected in the pancreas. ST4A1 is a brain-specific sulfotransferase believed to be involved in the metabolism of neurotransmitters. ST4A1 acts on catecholamines and T4 in a manner that may not involve sulfonation. ST4A1 may have a role in the metabolism of drugs and neurotransmitters in the CNS. In addition, ST4A1 is related to schizo...
TMPY-06110 ENTPD3 Protein, Mouse, Recombinant (His) Mouse Baculovirus-Insect Cells
TMPY-02340 HNMT Protein, Human, Recombinant (GST) Human E. coli
HNMT (Histamine N-methyltransferase) is a Protein Coding gene. This gene encodes the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. HNMT, the major enzyme for the metabolism of histamine in the rat brain, is potently inhibited by 9-amino-1,2,3,4-tetrahydroacridine (tacrine). Methylation is an important pathway in the biotransformation of many drugs, neurotransmitters, and xenobiotic compounds. Histamine N-methyltransferase (HNMT) catalyzes the N ...
TMPY-02639 ENTPD3 Protein, Human, Recombinant (His) Human Baculovirus-Insect Cells
TMPY-06324 Cadherin 17/CDH17 Protein, Human, Recombinant (His & AVI), Biotinylated Human HEK293
Cadherin-17 or LI-cadherin is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. Cadherin-17/LI-cadherin is a cadherin-like protein consisting of an extracellular region, 7 cadherin domains, and a transmembrane region but lacking the conserved cytoplasmic domain. The protein is a component of the gastrointestinal tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step in oral absorption of ...
TMPK-00805 CD117 Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293
The c-kit proto-oncogen (CD 117) has been shown to be present in several cell types including normal and neoplastic hemopoietic cells. Among normal BM cells, CD117 expression has been found in about half of the CD34 precursors including progenitors committed to the erythroid, granulo-monocytic, and megakaryocytic cell lineages.
TMPJ-00835 FGF-4 Protein, Mouse, Recombinant Mouse E. coli
Fibroblast growth factor 4(FGF-4) is a heparin binding member of the FGF family. The human FGF4 cDNA encodes 206 amino acids (aa) with a 33 aa signal sequence and a 173 aa mature protein with an FGF homology domain that contains a heparin binding region near the C-terminus. Mature human FGF4 shares 91%, 82%, 94% and 91% aa identity with mouse, rat, canine and bovine FGF4, respectively. Human FGF-4 has been shown to exhibit cross species activity. Expression of FGF-4 and its receptors, FGF R1c, 2...
TMPK-00947 CDH17/Cadherin 17 Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293
Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach.
TMPK-00952 CDH17/Cadherin 17 Domain 3 & 4 Protein, Human, Recombinant (mFc) Human HEK293
Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach.
TMPY-06656 C-Kit Protein, Human, Recombinant (His & AVI), Biotinylated Human HEK293
C-Kit is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). c-Kit contains 5 Ig-like C2-type (immunoglobulin-like) domains and 1 protein kinase domain. It belongs to the protein kinase superfamily, tyr protein kinase family, and CSF-1/PDGF receptor subfamily. C-Kit has tyrosine-protein kinase activity. Binding of the ligands leads to the autophosphorylation of KIT and its association with substrates such as phosphatidylinositol 3-kinase. Antibodies...

Recombinant Proteins

Hepatitis B Virus (HBV)(ayw/France/Tiollais/1979) Capsid protein (His)
TMPY-05822
Species: HBV
Source: E. coli
Azurocidin/CAP37 Protein, Human, Recombinant (His)
TMPY-00672
Species: Human
Source: HEK293
Cadherin 17/CDH17 Protein, Human, Recombinant (His)
TMPY-01912
Species: Human
Source: HEK293
C-Kit Protein, Human, Recombinant (His)
TMPY-01935
Species: Human
Source: HEK293
C-Kit Protein, Human, Recombinant (hFc)
TMPY-04051
Species: Human
Source: HEK293
ALK-1 Protein, Human, Recombinant (His)
TMPY-01168
Species: Human
Source: HEK293
FGF4 Protein, Human, Recombinant
TMPY-05004
Species: Human
Source: E. coli
Beta Defensin 3/DEFB103A Protein, Human, Recombinant (His)
TMPY-02835
Species: Human
Source: E. coli
CD117 Protein, Mouse, Recombinant (His)
TMPK-00777
Species: Mouse
Source: HEK293
CD117 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)
TMPK-01270
Species: Cynomolgus,Rhesus macaque
Source: HEK293
SULT4A1 Protein, Human, Recombinant
TMPJ-01296
Species: Human
Source: E. coli
ENTPD3 Protein, Mouse, Recombinant (His)
TMPY-06110
Species: Mouse
Source: Baculovirus-Insect Cells
HNMT Protein, Human, Recombinant (GST)
TMPY-02340
Species: Human
Source: E. coli
ENTPD3 Protein, Human, Recombinant (His)
TMPY-02639
Species: Human
Source: Baculovirus-Insect Cells
Cadherin 17/CDH17 Protein, Human, Recombinant (His & AVI), Biotinylated
TMPY-06324
Species: Human
Source: HEK293
CD117 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00805
Species: Human
Source: HEK293
FGF-4 Protein, Mouse, Recombinant
TMPJ-00835
Species: Mouse
Source: E. coli
CDH17/Cadherin 17 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00947
Species: Human
Source: HEK293
CDH17/Cadherin 17 Domain 3 & 4 Protein, Human, Recombinant (mFc)
TMPK-00952
Species: Human
Source: HEK293
C-Kit Protein, Human, Recombinant (His & AVI), Biotinylated
TMPY-06656
Species: Human
Source: HEK293
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TargetMol