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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T6514 | Glasdegib | PF-04449913 | Hedgehog/Smoothened , Smo |
Glasdegib (PF-04449913) (PF-04449913) is a potent, and orally bioavailable Smoothened (Smo) inhibitor with IC50 of 5 nM. Phase 2. | |||
T71455 | Glasdegib hydrochloride | ||
Glasdegib hydrochloride is a small-molecule inhibitor of the Hedgehog (Hh) signaling pathway with potential antineoplastic activity. | |||
T71453 | TriN2755 | ||
TriN2755 is a synthetic triazene derivative with antineoplastic activity. Upon metabolic activation via N-demethylation, TriN2755 is converted into highly reactive carbocations that can alkylate DNA and other macromolecu... |