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Search Results for " glasdegib "

Targets

3

Compounds

Cat No. Product Name Synonyms Targets
T6514 Glasdegib PF-04449913 Hedgehog/Smoothened , Smo
Glasdegib (PF-04449913) (PF-04449913) is a potent, and orally bioavailable Smoothened (Smo) inhibitor with IC50 of 5 nM. Phase 2.
T71455 Glasdegib hydrochloride
Glasdegib hydrochloride is a small-molecule inhibitor of the Hedgehog (Hh) signaling pathway with potential antineoplastic activity.
T71453 TriN2755
TriN2755 is a synthetic triazene derivative with antineoplastic activity. Upon metabolic activation via N-demethylation, TriN2755 is converted into highly reactive carbocations that can alkylate DNA and other macromolecu...
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