DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS

DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS is a fluorescent dye utilized as a fluorogenic substrate for aspartyl proteinase from the human malaria parasite [1]. It requires protection from light during storage.

Boc-Val-Pro-Arg-MCA TFA is a sensitive fluorescent substrate that is a thrombin substrate for the determination of trypsin-like serine protease activity.

H-Trp-Phe-Tyr-Ser(PO3H2)-Pro-Arg-pNA serves as a chromogenic substrate for Pin1, an essential and conserved mitotic peptidyl-prolyl isomerase that recognizes phosphoserine-proline bonds in mitotic phosphoproteins [1] [2].

Boc-Val-Pro-Arg-MCA hydrochloride (Boc-Val-Pro-Arg-MCA HCl) is a sensitive fluorescent substrate for the determination of trypsin-like serine proteases activity.

Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 (FS-6) is a quenched, fluorescent MMP peptide substrate designed for the real-time quantification of MMP enzymatic activity. As an extended variant of the MMP substrate (FS-1), it demonstrates increased specificity against collagenases (MMP-1, MMP-8, MMP-13) and MT1-MMP, evidenced by higher specificity constants (Ex/Em=325 nm/400 nm). [1]

Dabsyl-Leu-Gly-Gly-Gly-Ala-Edans is a fluorophore-labeled peptide with specificity for assaying the peptidase activity of the LasA protease from Pseudomonas aeruginosa, offering application value [1].

Arg-Val-(Nle-p-nitro)-Phe-Glu-Ala-Nle-NH2 is a fluorogenic substrate for the HIV-1 protease, facilitating the assessment of enzyme activity [1].

Z-Gly-Pro-Arg-4MβNA is a thrombin substrate that, upon cleavage by thrombin, releases 4-methoxy-2-naphthylamine (4MβNA). This liberated 4MβNA reacts with 5-nitrosalicylaldehyde to form an insoluble yellow fluorescent product, indicating the site of thrombin activity [1].

Z-Gly-Pro-Arg-AMC hydrochloride is a fluorescent substrate for both trypsin and cathepsin K, utilized to assay their respective enzymatic activities [1] [2].

Suc-Ala-Ala-Phe-AMC, a fluorogenic chymotrypsin substrate hydrolyzable by endopeptidase, has applications in vivo for assaying the acrosome reaction and in vitro for enzyme assays [1] [2] [3].

RE (EDANS) EVNLDAEFK (DABCYL) R is a double-labeled peptide with EDANS and DABCYL, functioning as a fluorescent substrate for BACE1 with an emission wavelength of 360 nm and an excitation wavelength of 528 nm. Its utility lies in the quantification of BACE1 activity, with the intensity of fluorescence being directly proportional to enzyme activity levels [1].

Cyclo(L-Phe-L-Pro) shows broad-spectrum antibacterial and antifungal activities. Cyclo(L-Phe-L-Pro) exhibits activity against methicillin-resistant S. aureus and Enterococcus raffinosus.