Cyanine-3

Sulfo-Cy3 diacid NHS ester is a CY3-derived dye. Cy3 (Sulfo-Cyanine3) is an amine-reactive cyanine orange dye with Ex/Em=550/570 nm, commonly used for fluorescent labelling of proteins and nucleic acids.

Sulfo-Cy3 amine, a dye derivative of Cyanine 3 (Cy3) with an amine group, features enhanced water solubility due to the sulfonate ion, making it ideal for aqueous solutions. Cy3 is a fluorescent dye emitting in the green to orange spectrum. The amine group can form covalent bonds with carboxyl groups, allowing Sulfo-Cy3 amine to bind to biological molecules like proteins and antibodies for tracking their location and dynamic changes in biological samples.

Sulfo-Cy3 hydrazide, a Cyanine 3 (Cy3) dye derivative, features hydrazine functionality and enhanced water solubility due to the presence of a sulfonate ion, making it ideal for aqueous solutions. Known for its fluorescence, Cy3 emits within the green to orange wavelength range. The hydrazide group enables hydrazinone coupling with aldehyde or ketone-bearing molecules, forming covalent bonds. This property allows Cy3 azide plus to attach to biomolecules, such as proteins and antibodies, for tracing their locations and dynamic changes in biological samples.

Sulfo-Cy3 NHS ester is a sulphonated CY3 derivative and fluorophore dye with an Ex/Em of 550/570 nm. Sulfo-Cy3 NHS ester is an amine-reactive fluorescent probe commonly employed for labelling nucleic acids and proteins.

CY3-YNE (Sulfo-Cyanine3-alkyne) is a dye labeled with a biomarker group alkyne, which can be used to label proteins, antibodies, peptides, nucleic acid molecules, and nanoparticles (Ex/Em: 554/566 nm).

Cy3 (Sulfo-Cyanine3) is an orange-fluorescent label for nucleic acids and proteins (λex=554, λem=568).

Cyanine3 NHS Ester Chloride is an amine-reactive orange-red fluorescent dye and the NHS ester derivative of Cyanine3, supplied as a chloride salt. Its N-hydroxysuccinimide (NHS) ester reacts efficiently with primary amines on proteins, antibodies, or other biomolecules under neutral to slightly basic conditions, forming stable amide bonds. This dye is widely used for cellular labeling, flow cytometry, and biomolecular staining studies.

Cyanine3 carboxylic acid is a non-toxic red fluorescent dye that serves as a non-reactive fluorophore for experimental controls and calibration. It can also be conjugated with targeting active molecules to create fluorescent probes for rapid detection of molecular reactions. [Ex/Em(nm)=550/570nm]

Alkyne is a commonly utilized biolabeling group. It forms stable bioconjugates with azide through a copper-catalyzed azide–alkyne cycloaddition (CuAAC) reaction. The excitation/emission (Ex/Em) wavelengths are 554/566 nm.

Cyanine3 NHS Ester Tetrafluoroborate is a fluorescent labeling reagent containing Cy3 fluorophore, NHS ester active group and tetrafluoroborate stabilizer. Cyanine3 NHS Ester Tetrafluoroborate can react with amino groups on biological molecules and is used in biological analysis fields such as protein, antibody, nucleic acid labeling and cell imaging.

Sulfo-cyanine3 azide TEA is a water-soluble cyanine dye and fluorescent probe (Ex/Em=548/563 nm). This compound can be involved in the synthesis of fused tricyclic heterocycles and the preparation of immune stimulants. It contains an Azide group, allowing it to undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing an Alkyne group. Additionally, it can participate in strain-promoted azide-alkyne cycloaddition (SPAAC) with molecules that have DBCO or BCN groups.

Sulfo-Cyanine3 Maleimide is an orange fluorescent dye containing a maleimide group that reacts specifically with thiol (-SH) groups on proteins, antibodies, and other biomolecules, forming stable thioether bonds in neutral buffers. The sulfonate modification imparts excellent water solubility, allowing labeling of solvent-sensitive or unstable proteins without organic co-solvents. This dye is widely used for fluorescence imaging, flow cytometry, and functional protein labeling studies.

Sulfo-Cyanine3 Trolox is a sulfonated orange fluorescent dye featuring a covalently attached Trolox moiety (a water-soluble vitamin E analog), which helps suppress photo-induced reactive oxygen species. This modification improves photostability and delays photobleaching while maintaining water solubility and biocompatibility. Sulfo-Cyanine3 Trolox is suitable for fluorescence imaging experiments requiring high photostability and may be adapted for certain super-resolution imaging applications depending on experimental conditions.

Cyanine3 amine hydrochloride, a potent green fluorescent dye and analog of Cyanine3 amine, features a primary amine group. This compound can be covalently coupled with reactive groups including NHS esters, carboxy groups (after carbodiimide activation), and epoxides. It exhibits an excitation wavelength (λ ex) of 555 nm and an emission wavelength (λ em) of 570 nm [1].

Cyanine3 carboxylic acid, a member of the cyanine dye series, is a widely used fluorescent marker for biomolecules and can interact with them. These dyes may also bind to double-helical DNA through intercalation, exhibiting enhanced fluorescence upon binding.

Cyanine3 hydrazide dichloride is a carbonyl-reactive dye that labels various carbonyl-containing molecules, including antibodies, glycoproteins (after periodate oxidation), proteins, or reducing sugars after oxidative stress or deamination [1].

Cyanine3 maleimide tetrafluoroborate is a specialized labeling reagent targeting sulfhydryl groups, characterized by an excitation wavelength (λ ex) of 550 nm and an emission wavelength (λ em) of 580 nm. It is applicable in the labeling of proteins and peptides [1] [2].

Sulfo-Cy3 maleimide potassium, a fluorescent dye, possesses a maleimide functionality at the end of a short alkyl linker and is utilized for labeling antibodies and other labile proteins [1].

Sulfo-cyanine3 azide is a water-soluble azide-containing cyanine dye and fluorescent probe (Ex/Em = 548/563 nm). The molecule contains an azide group, which can undergo copper-catalyzed azide‑alkyne cycloaddition (CuAAC) with alkyne-containing molecules, as well as strain-promoted alkyne‑azide cycloaddition (SPAAC) with molecules bearing DBCO or BCN groups.

Sulfo-cyanine3 azide sodium, a water-soluble azide cyanine dye and fluorescent probe (Ex/Em=548/563 nm), can be involved in the synthesis of fused tricyclic heterocycles and produces immunostimulatory agents [1] [2].

Sulfo-cyanine3 NHS ester sodium, a water-soluble cyanine dye, features NHS ester groups that are amino-reactive.

Cyanine 3 Bisfunctional MTSEA Dye potassium, part of the cyanine dye family, is a widely used fluorescent marker for biomolecules that interacts with them effectively. Cyanine dyes can also intercalate with double-helical DNA, exhibiting enhanced fluorescence upon binding.

Cyanine 3 DBCO chloride is a click chemistry reagent containing a cycloalkyne group. It serves as a linker for the Cyanine5.5 fluorophore. The DBCO group enables copper-free bioorthogonal click reactions with rapid kinetics and good stability (Ex/Em = 550/570 nm).

Cyanine 3 Tyramide (Tyramide-Cy3), an orange fluorescent dye, acts as a reporter substrate in horseradish peroxidase (HRP)-catalyzed deposition for signal amplification in immunoassays and in situ nucleic acid hybridization.