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By Target- Bcl-2 Family
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Results for "
BDA366
" in TargetMol Product Catalog- Inhibitors & Agonists1
bda-366
T67781909226-00-1
BDA-366, a potent Bcl2 antagonist, selectively binds the Bcl2-BH4 domain with high affinity (Ki = 3.3 nM), inducing a conformational change that nullifies its antiapoptotic function, thereby transforming it into a pro-apoptotic entity. This compound effectively suppresses lung cancer cell growth[1].
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