Amino-PEG5-amine

Amino-PEG5-amine, a PEG-based linker containing 5 units, is utilized in PROTAC synthesis.

Tri(Amino-PEG5-amide)-amine is a polyethylene glycol (PEG) derivative used as a PEG-based proteolysis targeting chimera (PROTAC) linker to aid in the synthesis of PROTACs[1].

Tetrazine-PEG5-SS-NHS ester is a PEG derivative composed of an NHS ester, which can react with amino acids or other amine-containing molecules.

Carboxy-Amido-PEG5-N-Boc is a PEG linker containing terminal carboxylic acid and Boc-protected amino groups. The hydrophilic PEG spacer enhances solubility in aqueous media. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g., EDC, HATU) to form stable amide bonds. The Boc group can be deprotected under mild acidic conditions to yield a free amine.