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By Target- Trk receptor
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Results for "
AZ23
" in TargetMol Product Catalog- Inhibitors & Agonists2
AZ-23
AZ 23, AZ23
T14363915720-21-7
AZ-23 is an inhibitor of ATP-competitive and Trk kinase A B C. For TrkA, TrkB, FGFR1, Flt3, Ret, MuSk, Lck, the IC50s values are 2 nM, 8 nM, 24 nM, 52 nM, 55 nM, 84 nM, 99 nM, respectively.
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NAZ2329
T634052809469-05-2
NAZ2329 is the first cell-permeable inhibitor of the R5 subfamily of receptor-type protein tyrosine phosphatases (RPTPs), which is a variant and preferentially inhibits PTPRZ (IC50=7.5 μM for hPTPRZ1) and PTPRG (IC50=4.8 μM for hPTPRG) compared to other PTPs. NAZ2329 inhibited the tumor growth of glioblastoma cells and exhibited stem cell-like properties compared to the whole (D1 + D2) fragment of PTPRZ.
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