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92950-39-5

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7-acetyl Paclitaxel
7-acetyl Taxol
T20134892950-39-5
7-acetyl Paclitaxel, serving as a microtubule depolymerization inhibitor, can prevent microtubule depolymerization caused by calcium ions at a concentration of 10 µM. Additionally, this compound significantly inhibits the growth of J774.2 macrophages (IC50 = ~60 nM) and elevates levels of nitric oxide (NO) and tumor necrosis factor (TNF) in isolated mouse peritoneal macrophages.
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