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9027-67-2

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Terminal deoxyribonucleotidyltransferase
TdT
TRP-003469027-67-2
Terminal deoxyribonucleotidyltransferase (TdT) catalyzes the addition of deoxyribonucleotide triphosphates to the 3' hydroxyl terminus of a DNA chain and introduces N regions at gene segment junctions during V(D)J recombination. It is expressed in immature, pre-B, and pre-T lymphocytes, as well as in acute lymphoblastic leukemia/lymphoma cells.
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