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By Target- Apoptosis
- Nrf2(1)
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Results for "
75483-04-4
" in TargetMol Product Catalog- Inhibitors & Agonists1
Nrf2 activator-10
T21001375483-04-4
Nrf2 activator-10 (Compound AI-1) is a PI3K-dependent antioxidant response element (ARE) inducer, with an EC50 of 2.7 μM, and also acts as an Nrf2 activator. It modifies Keap1, preventing the formation of the Cul3-Keap1 ubiquitin ligase complex, thereby activating Nrf2 transcription. Nrf2 activator-10 provides cellular protection against H2O2-induced apoptosis.
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