5b-cholanic acid-3a,6b,7b-triol

β-Muricholic acid (β-MCA) is a murine-specific primary bile acid.[1],[2] Dietary administration of β-MCA reduces HMG-CoA reductase activity in liver microsomes from mice fed a high cholesterol and cholic acid diet.[3] Dietary administration of β-MCA also dissolves 100% of gallstones in a gallstone-susceptible mouse model of diet-induced cholesterol gallstones.[4]

β-Muricholic Acid (Standard) is a reference standard for research and analysis in studies involving β-Muricholic Acid. β-Muricholic acid (β-MCA) is a primary bile acid unique to rodents. Administering β-MCA through diet can reduce the activity of HMG-CoA reductase in the liver microsomes of mice fed with high cholesterol and chenodeoxycholic acid diets. Giving β-MCA can also cause 100% of the cholesterol-containing gallstones in the diet-induced gallstone model to dissolve.