3-obaa

AM-9635 is a potent and selective PI3Kδ inhibitor. AM-9635 showes good cellular potency (in vitro pAKT IC50 = 4.2 nM ). AM-96352 inhibits KLH-specific IgG and IgM in a dosedependent manner AM-9635 is well tolerated at all doses and exhibits significantly reduced IgG and IgM specific antibodies . PI3Kα and PI3Kβ are ubiquitously expressed and play a role in cell growth, division, and survival.

OBAA is a phospholipase inhibitor and a broad-spectrum PLA2 inhibitor. It exhibits potent anti-inflammatory activity by blocking arachidonic acid pathways, used for acute inflammation research.