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1849590-01-7

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  • Inhibitors & Agonists
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    TargetMol | Activity
Tomivosertib
T34681849590-01-7
Tomivosertib (eFT508) is a potent and highly selective MNK1 and MNK2 inhibitor with an IC50 value of 1-2 nM.
  • $59
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TargetMol | Citations Cited
Tomivosertib HCl
T701241849590-02-8
Tomivosertib, also known as eFT508 is a MNK1/2 inhibitor. Tomivosertib binds to and inhibits the activity of MNK1 and 2. This prevents MNK1/2-mediated signaling, and inhibits the phosphorylation of certain regulatory proteins, including eukaryotic translation initiation factor 4E (eIF4E), that regulate the translation of messenger RNAs (mRNAs) involved in tumor cell proliferation, angiogenesis, survival and immune signaling.
  • $1,820
1-2 weeks
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