17 phenyl trinor prostaglandin f2α methyl ester

17-Phenyl trinor prostaglandin F2α glycinamide methyl ester is a derivative of Bimatoprost and functions as a prostaglandin analogue. This compound acts as an agonist for the human prostaglandin FP receptor. It exhibits ocular hypotensive effects and is utilized in research related to ocular hypertension and glaucoma.

Prostaglandin F2α (PGF2α) drives luteolysis and smooth muscle contraction by activating the FP receptor. Bimatoprost methyl ester is a lipophilic analog of 17-phenyl trinor PGF2α, a potent agonist for the FP receptor. 17-phenyl trinor PGF2α binds the FP receptor on ovine luteal cells with a relative potency of 756% compared to that of PGF2α. Esters of PGs serve as prodrugs, as they are efficiently hydrolyzed in certain tissues to generate the bioactive free acid.

Prostaglandin F2α (PGF2α), acting through the FP receptor, causes smooth muscle contraction and exhibits potent luteolytic activity. 17-trifluoromethylphenyl trinor PGF2α is an analog of PGF2α that shares the meta-trifluoromethyl group of travoprost with the 17-phenyl trinor modification of latanoprost. It is anticipated to be a potent and selective agonist of the FP receptor, with potential applications in glaucoma and luteolysis. 17-trifluoromethylphenyl trinor PGF2α methyl ester is a lipophilic analog of 17-trifluoromethylphenyl trinor PGF2α. Methyl esters of PGs serve as prodrugs, as they are efficiently hydrolyzed in certain tissues to generate the bioactive free acid.

1α-Monohomo-17-phenyl trinor Prostaglandin F2α (1α-Monohomo-17-phenyl trinor PGF2α) is a derivative of 17-phenyl trinor Prostaglandin F2α acetamide. Additionally, it is an isomer of 17-phenyl trinor Prostaglandin F2α methyl ester.