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1433820-83-7

" in TargetMol Product Catalog

Inhibitors & Agonists
1

GNE-431

T706681433820-83-7

GNE-431 is a potent, selective and noncovalent Btk inhibitor with IC50 of 3.2 nM. GNE-431 showed excellent potency against the C481R, T474I, and T474M mutants. GNE-431 may provide a treatment option to patients, especially those who have acquired resistance to ibrutinib by mutation of Cys481 or Thr474.

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$2,270

10-14 weeks

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