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By Target- BACE
- Beta Amyloid(1)
- Beta-Secretase(1)
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Results for "
1194044-20-6
" in TargetMol Product Catalog- Inhibitors & Agonists1
LY2811376
T26391194044-20-6
LY2811376, an orally available non-peptidic β-secretase(BACE1) inhibitor (IC50: 239-249 nM), can decrease Aβ secretion (EC50: 300 nM). It has 10-fold selectivity towards BACE1 over BACE2, and more than 50-fold inhibition over other aspartic proteases including pepsin, cathepsin D, or renin.
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