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Inhibitory Antibodies Inhibitory AntibodiesBiosimilar Antibody
Biosimilar Antibodies are antibody molecules that exhibit high similarity to established reference antibodies in terms of structural characteristics, physicochemical properties, and biological functions. Biosimilar Antibodies are primarily used in research settings for comparative studies and methodological evaluation, serving as research tools for consistency analysis, functional comparison, and assay validation.
Trastuzumab
Cited
T9912180288-69-1
Trastuzumab is a humanized monoclonal antibody for patients with invasive breast cancers that overexpress HER2. Trastuzumab has been clinically used to treat HER2 Positive Metastatic Breast Cancer and HER2 Positive Gastric Cancer.
- $157
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QTY
CitedCetuximab Cited
Cetuximab (anti-EGFR), C225
T9905205923-56-4
Cetuximab (C225) is a monoclonal antibody that is an inhibitor of human epidermal growth factor receptor (EGFR) (Kd=0.201 nM). Cetuximab has antitumor activity, inhibiting tumor cell proliferation and inducing apoptosis.
- $197
Size
QTY
CitedPembrolizumab
Pembrolizumab(anti-PD-1)
T99081374853-91-4
Pembrolizumab (MK-3475) is a highly selective humanized monoclonal antibody that antagonizes PD-1. It can block the PD-1 protein on T cells and prevent their interaction with PD-L1 on cancer cells.
- $218
Size
QTY
Bevacizumab Cited
T9904216974-75-3
Bevacizumab, a humanized monoclonal antibody, specifically and with high affinity binds to all isoforms of VEGF-A.
- $129
Size
QTY
CitedAtezolizumab Cited
T99021380723-44-3
Atezolizumab is an antibody inhibitor, a humanized monoclonal antibody, IgG1, which targets PD-L1 and blocks the interaction of PD-L1 with PD-1. Atezolizumab has antitumor activity and promotes T-cells to attack tumor cells.
- $228
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QTY
CitedAmivantamab (Anti-c-Met)
JNJ61186372 (Anti-c-Met), JNJ-61186372 (Anti-c-Met), JNJ 61186372 (Anti-c-Met)
T77110
Amivantamab (Anti-c-Met) is a human antibody that recognizes the MET proto-oncogene (MET) and can be used in cancer-related research.
- $289
Size
QTY
Dupilumab
SAR-231893, REGN-668
T136661190264-60-8
Dupilumab (REGN-668) is a fully human monoclonal antibody targeting the alpha subunit of the interleukin-4 receptor, thereby inhibiting IL-4 and IL-13 signaling. As a systemic immunomodulator, it has demonstrated efficacy in improving atopic dermatitis.
- $239
Size
QTY
Evolocumab
T99201256937-27-5
Evolocumab is an inhibitor of the humanized monoclonal antibody PCSK9. It binds to circulating PCSK9 protein, resulting in inhibition of PCSK9 binding to LDLR. It can be used in studies of hypercholesterolemia and atherosclerotic cardiovascular disease.
- $323
Size
QTY
Tezepelumab
Tezepelumab-ekko, MEDI 19929, AMG 157
T773591572943-04-4
Tezepelumab (AMG 157) is a humanized monoclonal antibody (IgG2λ) targeting TSLP that prevents TSLP from interacting with its heterodimer receptor. Tezepelumab can be used to study advanced asthma disease.
- $1,060
Size
QTY
Nivolumab Cited
T9907946414-94-4
Nivolumab is a monoclonal antibody and is a humanized PD-1 antibody. Nivolumab has anti-tumor activity and is used in the treatment of melanoma, non-small cell lung cancer, renal cell carcinoma, etc.
- $182
Size
QTY
CitedInfliximab Cited
T9921170277-31-3
Infliximab is a monoclonal antibody, a human-mouse chimeric monoclonal antibody that inhibits TNF-α and prevents TNF-α from interacting with TNFR1 and TNFR2. Infliximab can be used to treat Crohn's disease and rheumatoid arthritis.
- $98
Size
QTY
CitedMagrolimab
Magrolimab (anti-CD47), Hu5F9-G4
T353902169232-81-7
Magrolimab (Hu5F9-G4) is a humanized anti-CD47 IgG4 monoclonal antibody that exhibits antitumor activity by blocking CD47 and binding primarily to the N-terminal pyroglutamate of CD47. It can be used in combination with other compounds for the treatment of recurrent myeloma.
- $163
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QTY
Avelumab
T99031537032-82-8
Avelumab, a fully human IgG1 anti-PD-L1 monoclonal antibody, exhibits potential antibody-dependent cell-mediated cytotoxicity.
- $289
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QTY
Adalimumab Cited
T9901331731-18-1
Adalimumab (anti-TNF-alpha) is the first fully human recombinant IgG1 monoclonal antibody that specifically targets human TNF-alpha.
- $213
Size
QTY
CitedAducanumab
BIIB037
T770421384260-65-4
Aducanumab (BIIB037), A selective human immunoglobulin gamma-1 (IgG1) monoclonal antibody, targets the clustered form of amyloid beta (Aβ). Aducanumab shows brain permeability and may be used to treat Alzheimer's disease (AD).
- $189
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Brentuximab
T767182088770-90-3
Brentuximab, a chimeric antibody targeting CD30, is a naked antibody to Brentuximab vedotin. It possesses antitumor activity and may be used to study relapsed or refractory Hodgkin's lymphoma.
- $297
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QTY
Alirocumab
T99161245916-14-6
Alirocumab is a human monoclonal antibody that inhibits PCSK9. It is produced by recombinant DNA technology in Chinese hamster ovary cell suspension culture.
- $247
Size
QTY
Teneliximab
Chi220, BMS 224819, Anti-Human CD40 Recombinant Antibody
T76830299423-37-3
Teneliximab (BMS 224819) is a chimeric monoclonal antibody and a tumor necrosis factor receptor superfamily member 5 (CD40) inhibitor that blocks CD40-CD40L interactions.Teneliximab exerts its partial agonist activity through CD40 and peripheral B-cell depletion, and may be used to study organ transplant rejection and rheumatoid arthritis.
- $98
Size
QTY
Abelacimab
MAA868, MAA 868
T768942098724-83-3
Abelacimab (MAA868), a fully human IgG1 monoclonal antibody that binds to and blocks the activation of FXI, is an anticoagulant used in the study of thromboembolic diseases.
- $228
Size
QTY
Opicinumab
BIIB033
T774161422268-07-2
Opicinumab (BIIB033) is a novel monoclonal antibody against LINGO-1 that may be used to prevent and delay acute optic neuritis and recurrent multiple sclerosis.
- $198
Size
QTY
Telisotuzumab
Mab-224G11, ABT-700
T774371781223-80-0
Telisotuzumab(ABT-700) is a humanized recombinant antibody targeting the therapeutic hepatocyte growth factor receptor (MET) with high affinity for c-Met.Telisotuzumab has inhibitory effects on c-Met signaling and antitumor activity.
- $372
Size
QTY
Sacituzumab
Sacituzumab (anti-Trop-2), Sacituzumab
T353971796566-95-4
Sacituzumab is a humanized IgG1 monoclonal antibody utilized in the synthesis of antibody-active small-molecule couplings (naked antibody to Sacituzumab govitecan). It exhibits potential antitumor activity and is employed in tumor research.
- $163
Size
QTY
Rituximab Cited
T9910174722-31-7
Rituximab is an anti-CD20 chimeric monoclonal antibody used to study certain autoimmune diseases and cancers.
- $229
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QTY
CitedMonalizumab
T766911228763-95-8
Monalizumab is a novel immune checkpoint inhibitor targeting natural killer cell population 2A (NKG2A). Monalizumab is a humanized monoclonal antibody against NKG2A that induces IFN-γ production, thereby activating natural killer cell function. Monalizumab has antitumor activity and can be used to study neck squamous cell carcinoma (HNSCC).
- $243
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