T78971 |
AMPA receptor modulator-4
|
2917551-59-6
|
98%
|
|
AMPA Receptor Modulator-4, a 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide (BTD), serves as an orally active positive allosteric modulator of the AMPA recept...
|
T79191 |
AMPA receptor modulator-5
|
2034182-22-2
|
98%
|
|
AMPA Receptor Modulator-5 (Example 217) serves as an AMPA receptor modulator, utilized in neurological disease research [1].
|
T79273 |
NMDA receptor antagonist 6
|
|
98%
|
|
NMDA Receptor Antagonist 6 (Compound 13b) functions as an antagonist at the glycine-binding site of the NMDA receptor and demonstrates cytoneuroprotective effica...
|
T79374 |
NMDA receptor antagonist 7
|
|
98%
|
|
Compound (S)-10a, a GluN2B subunit-selective NMDA receptor antagonist, exhibits a K i of 93 nM and an IC 50 of 72 nM. It is potentially useful for research into ...
|
T79375 |
NMDA receptor antagonist 8
|
|
98%
|
|
Compound (R)-10a, an NMDA receptor antagonist, exhibits selectivity for the GluN2B subunit, possessing a Ki of 265 nM and an IC50 of 62 nM. This compound is util...
|
T79504 |
AMPA receptor modulator-6
|
516491-33-1
|
98%
|
|
AMPA receptor modulator-6, an AMPA receptor positive allosteric modulator (PAM), is utilized in the research of neurological diseases [1].
|
T79611 |
DQP-26
|
1449373-99-2
|
98%
|
|
DQP-26, a potent negative allosteric modulator of NMDA receptors (NMDARs), exhibits IC50 values of 0.77 μM for GluN2C and 0.44 μM for GluN2D subunits, indicating...
|
T79855 |
Nevadistinel
|
2181816-92-0
|
98%
|
|
Nevadistinel (NYX-458; NYX-3054) is a positive allosteric modulator of the N-methyl-D-aspartate (NMDA) receptor, indicated for mitigating cognitive deficits rela...
|
T79857 |
Risevistinel
|
2591344-26-0
|
98%
|
|
Risevistinel (NYX-783), a positive allosteric modulator of the N-methyl-D-aspartate (NMDA) receptor, may mitigate cognitive deficits in neurodegenerative conditi...
|
T79959 |
6-Hydroxykynurenic acid
|
3778-29-8
|
98%
|
|
6-Hydroxykynurenic acid (6-HKA), a kynurenic acid (KYNA) derivative isolated from Ginkgo leaves, functions as a low-affinity NMDAR antagonist with an IC50 of 59 ...
|
T81409 |
Pregnanolone sulfate (pyridinium)
|
124107-39-7
|
98%
|
|
Pregnanolone sulfate pyridinium, an endogenous neurosteroid, inhibits NMDA receptors and exhibits neuroprotective properties [1].
|
T81899 |
LY836
|
|
98%
|
|
LY836 is an orally active, neuroprotective compound that effectively inhibits the PSD95-nNOS association in cortical neurons. It has potential applications in th...
|
T81912 |
LSP-GR3
|
1235945-37-5
|
98%
|
|
LSP-GR3, a novel splice modulating oligomer (SMO) consisting of chemically-modified RNA oligonucleotides, potently and specifically directs the alternative splic...
|
T16800 |
(RS)-AMPA
|
77521-29-0
|
98%
|
|
(RS)-AMPA ((±)-AMPA) is a glutamate analog. (RS)-AMPA is an agonist of effective and selective excitatory neurotransmitter L-glutamic acid.
|
T15684 |
L-689560
|
139051-78-8
|
98%
|
|
L-689560 is widely used as a radiolabeled ligand in binding studies and used to study the roles of NMDA receptors in normal neurological processes as well as in ...
|
T23490 |
UBP310
|
902464-46-4
|
98%
|
|
UBP310 (UBP 310) is a GLUK5 kainate receptor antagonist
|
T5819 |
Rapastinel Trifluoroacetate
|
1435786-04-1
|
99.96%
|
|
Rapastinel Trifluoroacetate (GLYX-13 Trifluoroacetate) is an NMDA receptor modulator with glycine-site partial agonist properties.
|
T3320 |
Dizocilpine Maleate
|
77086-22-7
|
99.96%
|
|
Dizocilpine Maleate (MK 801) is a potent noncompetitive antagonist of the NMDA receptor (RECEPTORS, N-METHYL-D-ASPARTATE) with Kd of 37.2 nM in rat brain membran...
|
T4979 |
Procyclidine hydrochloride
|
1508-76-5
|
99.95%
|
|
Procyclidine hydrochloride ((±)-Procyclidine hydrochlorid) is a potent anticholinergic agent and also have NMDA antagonist properties.
|
T16402 |
Org-26576
|
1026791-61-6
|
99.94%
|
|
Org-26576 is a positive allosteric modulator of the AMPA receptor.
|