T6594 |
MNS
|
1485-00-3
|
98%
|
|
MNS is a tyrosine kinases inhibitor, inhibits Syk, Src, p97 with IC50 of 2.5 μM, 29.3 μM and 1.7 μM, respectively.
|
T23128 |
PD180970
|
287204-45-9
|
98%
|
|
PD180970 is an inhibitor of Bcr-Abl with IC50s of 5 nM, 0.8 nM and 50 nM for the autophosphorylation of p210Bcr-Abl, Src and Kit. PD180970 can be used in studies...
|
T37603L |
Osteogenic Growth Peptide (10-14) acetate
|
|
98%
|
|
Osteogenic Growth Peptide (10-14) acetate is a Src inhibitor and an effective mitogen and stimulator of osteogenesis and hematopoiesis. Osteogenic Growth Peptide...
|
T23176 |
PP 3
|
5334-30-5
|
98%
|
|
PP 3 is a Negative control for the Src kinase inhibitor PP 2
|
T17267 |
XL228
|
898280-07-4
|
98%
|
|
XL228 is an inhibitor of multi-targeted tyrosine kinase (IC50s: 5, 3.1, 1.6, 6.1, 2 nM for Bcr-Abl, Aurora A, IGF-1R, Src, and Lyn, respectively).
|
T6732 |
WYE-687
|
1062161-90-3
|
98%
|
|
WYE-687 is an ATP-competitive and selective inhibitor of mTOR with IC50 of 7 nM; blocks mTORC1/pS6K(T389) and mTORC2/P-AKT(S473) but no effect observed on P-AKT(...
|
T6315 |
MLN8054
|
869363-13-3
|
98%
|
|
MLN8054 is a potent and selective Aurora A kinase inhibitor with an IC50 of 4 nM.
|
T2709 |
TAK-901
|
934541-31-8
|
98%
|
|
TAK-901 has been used in trials studying the treatment of Lymphoma, Myelofibrosis, Multiple Myeloma, Myeloid Metaplasia, and Advanced Solid Tumors, among others....
|
T6077 |
ZM-447439
|
331771-20-1
|
98%
|
|
ZM 447439 is a selective and ATP-competitive inhibitor for Aurora A and Aurora B with IC50 of 110 nM and 130 nM, respectively. It is more than 8-fold selective f...
|
T6419 |
BMS-536924
|
468740-43-4
|
98%
|
|
BMS-536924 is an ATP-competitive IGF-1R/IR inhibitor with IC50 of 100 nM/73 nM, modest activity for Mek, Fak, and Lck with very little activity for Akt1, MAPK1/2...
|
T2153 |
1-NM-PP1
|
221244-14-0
|
98%
|
|
1 nM-PP1 is a cell-permeable PP1 analog that acts as a potent and selective inhibitor of mutant kinases over their wild-type progenitors.
|
T13824 |
PP58
|
212391-58-7
|
98%
|
|
PP58 is an inhibitor of PDGFR, FGFR and Src family.
|
T2070 |
Agerafenib
|
1188910-76-0
|
98%
|
|
CEP-32496 is a highly potent inhibitor of BRAF.
|
T8995 |
NCGC00262650
|
344359-25-7
|
98%
|
|
NCGC00262650 is an inhibitor of AMA1-RON2 interaction and c-Src tyrosine kinase activity.
|
T23127 |
PD-161570
|
192705-80-9
|
98%
|
|
FGFR inhibitor
|
T6982 |
SGI-7079
|
1239875-86-5
|
98%
|
|
SGI-7079 is a new selective Axl inhibitor. SGI-7079 can be a dose-dependent manner inhibited growth of tumors. It is also a potential therapeutic target for EGFR...
|
T16760 |
RK-24466
|
213743-31-8
|
98%
|
|
RK-24466 is a selective and potent inhibitor of Lck, inhibits Lck (64-509) and LckCD isoforms with IC50s of less than 1 and 2 nM, respectively.
|
T3063 |
PD173955
|
260415-63-2
|
98%
|
|
PD173955 is src family-selective tyrosine kinase inhibitor with IC50 of ~22 nM for Src, Yes and Abl kinase; less potent for FGFRα and no activity on InsR and PKC...
|
T1754 |
ZM 306416
|
690206-97-4
|
98%
|
|
ZM 306416, a VEGFR1 inhibitor (IC50: 0.33 μM), can also inhibit EGFR (IC50<10 nM).
|
T6057 |
URMC-099
|
1229582-33-5
|
98%
|
|
URMC-099 is an orally bioavailable, brain penetrant MLK inhibitor (IC50: 19/42/14/150 nM, for MLK1/MLK2/MLK3/DLK), and also inhibits LRRK2 activity (IC50: 11 nM)...
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