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(1)
By Target- E1/E2/E3 Enzyme
- MDM-2/p53(1)
- Target Protein Ligand-Linker Conjugate(1)
- Others(1)
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Results for "
target/Mdm2/1
" in TargetMol Product Catalog- Inhibitors & Agonists2
- PROTAC Products1
- Recombinant Protein2
BI-0252
T145541818291-27-8
BI-0252 is an inhibitor of MDM2-p53 (IC50:4 nM). BI-0252 can induce tumor regressions in all animals of a mouse SJSA-1 xenograft. And it concomitant induction of the tumor protein p53 (TP53) target genes and markers of apoptosis.
- $1,820
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(Rac)-PROTAC PARP/EGFR ligand 1
T2081772935073-36-0
(Rac)-PROTAC PARP/EGFR ligand 1 is a compound that includes ligands for target proteins PARP and EGFR, along with a PROTAC linker that recruits E3 ligases such as VHL, CRBN, MDM2, and IAP. It is utilized in the synthesis of PROTAC DP-C-4, a dual CRBN-based PROTAC designed for the concurrent degradation of EGFR and PARP.
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