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(1)
By Target- Akt
- Apoptosis(1)
- Autophagy(1)
- JNK(1)
- PDK(1)
- mTOR(1)
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- cAMP
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- CaSR
- CGRP Receptor
- cholecystokinin
- CRFR
- CXCR
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- GPR
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- GTPase
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Results for "
target/JNK/1
" in TargetMol Product Catalog- Inhibitors & Agonists1
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- Recombinant Protein4
Polyphyllin I
Cited
T389550773-41-6
Polyphyllin D induces apoptosis via the mitochondrial apoptotic pathway as evidenced by decreased Bcl-2 expression levels, disruption of MMP and increased Bax, cytochrome C, and cleaved-caspase-3 levels. Polyphyllin D has an anti-angiogenic effect. Polyphyllin D has toxicity in human RBCs as well as its underlying mechanism for the hemolysis and eryptosis/erythroptosis. Polyphyllin D has strong anticancer activity, can overcome drug resistance in R-HepG2 cells and elicit programmed cell death via mitochondrial dysfunction.
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