T16500 |
PF-3450074
|
1352879-65-2
|
99.92%
|
|
PF-3450074 (PF-74) acts at an early stage of HIV-1 infection inhibits viral replication by directly competing with the binding of CPSF6 (nuclear host factors cle...
|
T11451 |
GPI-1046
|
186452-09-5
|
99.91%
|
|
GPI-1046 is an immunophilin ligand without antibiotic action and attenuates ethanol intake in part through the upregulation of glutamate transporter 1 (GLT1) in ...
|
T1416 |
Zidovudine
|
30516-87-1
|
99.91%
|
|
Zidovudine (ZDV) is a synthetic dideoxynucleoside. After intracellular phosphorylation to its active metabolite, zidovudine inhibits DNA polymerase, resulting in...
|
TP1149 |
HIV-1 Rev (34-50)
|
141237-50-5
|
99.91%
|
|
HIV-1 Rev (34-50) (HIV-1 rev Protein (34-50)) is a 17 amino acid peptide with anti-HIV-1 activity. HIV-1 Rev (34-50) is derived from the Rev-responsive element-b...
|
T9063 |
Clathrin-IN-1
|
1332879-52-3
|
99.91%
|
|
Clathrin-IN-1 is a inhibitor of clathrin, and inhibits clathrin-mediated endocytosis (CME) by associating with the terminal domain of clathrin. It has the potent...
|
T31860L |
(Iso)-Fosdevirine
|
2869918-45-4
|
99.90%
|
|
(Iso)-Fosdevirine ( (Iso)-GSK2248761) is a selective and potent non-nucleoside reverse transcriptase (NNRTI) inhibitor with anti-HIV activity for the study of ne...
|
T67798 |
(2RS)-FPMPA
|
135295-27-1
|
99.90%
|
|
(2RS)-FPMPA(FPMPA) has antiviral activity with an IC50 value of 1.85 μM measured in human MT12 cells infected with SHIV (DH4R).
|
T1743 |
Aprepitant
|
170729-80-3
|
99.9%
|
|
Aprepitant (Aprepitant`) is a Substance P/Neurokinin-1 Receptor Antagonist. The mechanism of action of aprepitant is as a Neurokinin 1 Antagonist, and Cytochrome...
|
T15210 |
Elsulfavirine
|
868046-19-9
|
99.89%
|
|
Elsulfavirine (VM-1500) is an HIV-1 infection reverse transcriptase inhibitor. It is a new anti-HIV drug.
|
T16154 |
MS417
|
916489-36-6
|
99.88%
|
|
MS417 (GTPL7512) is an inhibitor of BET-specific BRD4(BRD4-BD1 and BRD4-BD2 with IC50s of 30, 46 nM and Kds of 36.1, 25.4 nM, respectively), with weak selectivit...
|
T2615 |
Flavopiridol hydrochloride
|
131740-09-5
|
99.88%
|
|
Flavopiridol hydrochloride (MDL 107826A) is a synthetic N-methylpiperidinyl chlorophenyl flavone compound. As an inhibitor of cyclin-dependent kinase, alvocidib ...
|
T6377 |
Aloperine
|
56293-29-9
|
99.88%
|
|
Aloperine exhibits anti-inflammatory, antibacterial, antiviral, and anti-tumor properties.
|
T13974 |
ZL0580
|
2377151-10-3
|
99.87%
|
|
ZL0580 induces HIV suppression by inhibiting Tat transactivation and transcription elongation as well as by inducing repressive chromatin structure at the HIV pr...
|
T2409L |
Tenofovir Disoproxil Fumarate
|
202138-50-9
|
99.86%
|
|
Tenofovir Disoproxil Fumarate (GS-1278 Disoproxil Fumarate) is a pro-drug, fumaric acid salt form of tenofovir, a nucleoside reverse transcriptase inhibitor anal...
|
T10133 |
3'-Azido-3'-deoxy-5-methylcytidine
|
1282040-14-5
|
99.86%
|
|
3'-Azido-3'-deoxy-5-methylcytidine inhibits HIV-1 reverse transcriptase(EC50 = 0.06 μM) and is an effective inhibitor of xenotropic murine leukemia-related retro...
|
T39755 |
Pirmitegravir
|
2245231-10-9
|
99.86%
|
|
Pirmitegravir (STP0404) is a potent and selective inhibitor of allosteric integrase (ALLINI) targeting the LEDGF/p75 binding site. Pirmitegravir inhibits PBMC. P...
|
T3614 |
Inosine pranobex
|
36703-88-5
|
99.85%
|
|
Inosine pranobex (Delimmun) has a number of immunomodulatory effects, including inducing T-lymphocyte differentiation, augmenting macrophage and NK cell function...
|
T6367 |
Abacavir sulfate
|
188062-50-2
|
99.85%
|
|
Abacavir sulfate (Ziagen) , a nucleoside analogue, effectively utilize its antiviral activity
|
T6837 |
Flavopiridol
|
146426-40-6
|
99.85%
|
|
Flavopiridol (Alvocidib) (Alvocidib) competes with ATP to inhibit CDKs including CDK1, CDK2, CDK4 and CDK6 with IC50 of ~ 40 nM. It is 7.5-fold more selective fo...
|
T7991 |
2-Hydroxycinnamic acid
|
614-60-8
|
99.83%
|
|
2-Hydroxycinnamic acid is a natural product isolated from Angraecum fragrans, has photooxidant activity.
|