T1776 |
Plerixafor
|
110078-46-1
|
100%
|
|
Plerixafor (AMD-3329), a chemokine receptor antagonist, blocks the binding of stromal cell-derived factor (SDF-1alpha) to the cellular receptor CXCR4.
|
T28255 |
Opaviraline
|
178040-94-3
|
100%
|
|
Opaviraline (GW-420867X) is a potent reverse transcriptase inhibitor that inhibits Human immunodeficiency virus 1 and has the potential to treat HIV infection.
|
TJS1779 |
Protosappanin A
|
102036-28-2
|
100%
|
|
Protosappanin A (PTA) has anti-oxidative/nitrative activities on brain immune and neuroinflammation through regulation of CD14/TLR4-dependent IKK/IκB/NF-κB inf...
|
T2279 |
Tizoxanide
|
173903-47-4
|
100%
|
|
Tizoxanide (Desacetyl-nitazoxanide) is a metabolite of lamivudine. Lamivudine (2', 3'-dideoxy-3'-thiacytidine, commonly called 3TC) is a potent nucleoside analog...
|
T27625 |
IQP-0528
|
301297-45-0
|
100%
|
|
IQP-0528 is a potent non-nucleoside reverse transcriptase inhibitor (NNRTI) that has potential for the treatment of HIV infection by blocking viral entry and sho...
|
T3323 |
Ursonic Acid
|
6246-46-4
|
100%
|
|
Ursonic Acid (TOS-BB-0966) belongs to the family of Ursane Triterpenes whose structure is based on the pentacyclic ursane skeleton. It has potential as HIV-1 Pro...
|
T7624 |
DAPTA
|
106362-34-9
|
100%
|
|
DAPTA (Adaptavir) is an inhibitor of CCR5, shows potent anti-HIV activities.
|
T6367 |
Abacavir sulfate
|
188062-50-2
|
100%
|
|
Abacavir sulfate (Ziagen) , a nucleoside analogue, effectively utilize its antiviral activity
|
T7903 |
Saquinavir
|
127779-20-8
|
100%
|
|
Saquinavir (Ro 31-8959) is a potent HIV protease inhibitor, is an antiretroviral drug used together with other medications to treat or prevent HIV/AIDS.
|
T1525 |
Ritonavir
|
155213-67-5
|
100%
|
|
Ritonavir (ABT 538) is a peptidomimetic agent that inhibits both HIV-1 and HIV-2 proteases. Ritonavir is highly inhibited by serum proteins but boosts the effect...
|
T5863 |
Indinavir sulfate
|
157810-81-6
|
100%
|
|
Indinavir sulfate (L735524 sulfate) is a HIV protease inhibitor.It inhibits the HIV-1 protease with an IC50 value of 0.41 nM and Ki value of 0.24 nM.
|
T6016 |
Maraviroc
|
376348-65-1
|
100%
|
|
Maraviroc (Selzentry) is a C-C Chemokine Receptor Type 5 (CCR5) antagonist, and for MIP-1α(IC50=3.3 nM), MIP-1β (IC50=7.2 nM) and RANTES(IC50=5.2 nM).Maraviroc i...
|
T6065 |
Triciribine
|
35943-35-2
|
100%
|
|
Triciribine (NSC-154020) is a DNA synthesis inhibitor, and it also inhibits Akt and HIV-1/2.
|
T24362 |
L 756423
|
216863-66-0
|
100%
|
|
L 756423 (L756423) is a novel potent and selective and competitive HIV protease inhibitor with a Ki value of 0.049 nM for HIV-1 PR.L 756423 blocks the spread of ...
|
T11538 |
Hck-IN-1
|
1473404-51-1
|
|
|
Hck-IN-1 is a selective Nef-dependent Hck inhibitor (IC50s: 2.8 μM and >20 μM for Nef:Hck complex and Hck) with antiretroviral activity. Hck-IN-1 is a direct and...
|
T16791 |
Rottlerin
|
82-08-6
|
|
|
Rottlerin (NSC-56346) is a natural product purified from Mallotus Philippinensis and is a specific PKC inhibitor (IC50: PKCδ of 3-6 μM, PKCα,β,γ of 30-42 μM, PKC...
|
T3060 |
Fasudil hydrochloride
|
105628-07-7
|
|
|
Fasudil hydrochloride (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK with Ki of 0.33 μM, 1.0 μM, 9.3 μM and 55 μM, respectively.
|
T4S1999 |
Valepotriate
|
18296-44-1
|
|
|
Valepotriate (Valtrate) fraction can have sedative effects and affect behavioral parameters related to recognition memory. Valepotriates, a new class of cytotoxi...
|
T2830 |
Betulinic acid
|
472-15-1
|
|
|
Betulinic acid (ALS-357) is a pentacyclic lupane-type triterpene derivative of betulin (isolated from the bark of Betula alba, the common white birch) which has ...
|
T9632 |
CDK9-IN-30
|
748146-89-6
|
98%
|
|
CDK9-IN-30 is one of the Tat peptide derivatives and inhibits HIV-1 long terminal repeat-activated transcription.
|