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Dopamine Receptor

Dopamine receptors are a class of G protein-coupled receptors that are prominent in the vertebrate central nervous system (CNS). Dopamine receptors activate different effectors through not only G-protein coupling, but also signaling through different protein (dopamine receptor-interacting proteins) interactions.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T6647 Rotigotine- 99755-59-6 99.76%
Rotigotine-
Rotigotine (N-0923) is a non-ergot dopamine receptor agonist used in the therapy of Parkinson disease and restless leg syndrome. Administered as a once-daily tra...
T0025 Haloperidol 52-86-8 99.76%
Haloperidol
Haloperidol (Serenace) is a highly potent neuroleptic by relieving nervous through the depression of nerve function. In addition, haloperidol has shown about 50-...
T28435 PNU-96391 146798-66-5 99.76%
PNU-96391
PNU-96391 (OSU-6162) is an antagonist of dopamine D2 and a partial agonist of 5-HT2A. PNU-96391 can be used in research on the treatment of chronic diseases.
T1552 Itopride hydrochloride 122892-31-3 99.76%
Itopride hydrochloride
Itopride hydrochloride (Ganaton) is an AChE and D2DR inhibitor.
T4297 Flibanserin 167933-07-5 99.76%
Flibanserin
Flibanserin (Girosa) is a serotonergic antidepressant used to treat hypoactive sexual desire disorder. Flibanserin has been associated with a low rate of minor s...
T1644 Dopamine hydrochloride 62-31-7 99.76%
Dopamine hydrochloride
Dopamine hydrochloride (ASL279) is a naturally occurring catecholamine formed by decarboxylation of dihydroxyphenylalanine and a precursor of norepinephrine and ...
T4577 Cariprazine 839712-12-8 99.75%
Cariprazine
Cariprazine (RGH-188) is a novel antipsychotic drug candidate that exhibits high affinity for the D3 (Ki=0.085 nM) and D2 (Ki=0.49 nM) receptors, and moderate af...
T5858 Sertindole 106516-24-9 99.74%
Sertindole
Sertindole (Lu 23-174) is an atypical antipsychotic that binds to dopamine D2 receptors and the serotonin (5-HT) receptor subtypes 5-HT1D, 5-HT2A, and 5-HT2C (Kd...
T0766 Promazine hydrochloride 53-60-1 99.74%
Promazine hydrochloride
Promazine hydrochloride (Romtiazin hydrochloride) is a phenothiazine with actions similar to CHLORPROMAZINE but with less antipsychotic activity. It is primarily...
T1517 Benserazide hydrochloride 14919-77-8 99.74%
Benserazide hydrochloride
Benserazide hydrochloride (Ro 4-4602) is a peripherally-acting L-amino acid decarboxylase (AAAD) or DOPA decarboxylase inhibitor.
T0082 Domperidone 57808-66-9 99.73%
Domperidone
Domperidone (R33812)(Motilium) is a dopamine blocker and an antidopaminergic reagent. It blocks the action of. It has strong affinities for the D2 and D3 dopamin...
T7834 ABT-724 70006-24-5 99.73%
ABT-724
ABT-724 is an agonist of dopamine D4 receptor(EC50: 12.4 nM)
T0302 Triflupromazine hydrochloride 1098-60-8 99.73%
Triflupromazine hydrochloride
Triflupromazine hydrochloride (Fluopromazine hydrochloride), an antipsychotic medication, is Dopamine D1/D2 receptor antagonists.
T20968 CyPPA 73029-73-9 99.72%
CyPPA
CyPPA, a subtype-selective positive modulator of SK channels, decreased spontaneous firing rate, increased the duration of the apamin-sensitive afterhyperpolariz...
T22019 ABT 724 trihydrochloride 587870-77-7 99.72%
ABT 724 trihydrochloride
ABT 724 trihydrochloride is an effective and selective agonist of the D4 receptor (EC50 = 12.4 nM, 14.3 nM, and 23.2 nM for human, rat and ferret, respectively)....
T0162 Quetiapine 111974-69-7 99.71%
Quetiapine
Quetiapine (ICI204636) is used for the therapy of schizophrenia, and for the treatment of acute manic episodes associated with bipolar I disorder. The mechanism ...
T1327 Nortriptyline hydrochloride 894-71-3 99.71%
Nortriptyline hydrochloride
Nortriptyline hydrochloride (ELF-101 hydrochloride) is a metabolite of AMITRIPTYLINE that is also used as an antidepressive agent. Nortriptyline is used in major...
T2574 Alizapride hydrochloride 59338-87-3 99.71%
Alizapride hydrochloride
Alizapride hydrochloride (Alizapride HCl) is a dopamine receptor antagonist used for the treatment of nausea and vomiting.
T15117 Didesmethyl cariprazine 839712-25-3 99.70%
Didesmethyl cariprazine
Didesmethyl cariprazine, a metabolite of Cariprazine, is the major cyclic active part. Didesmethyl cariprazine has a long half-life of 1-3 weeks. Cariprazine is ...
T5387 LP-211 1052147-86-0 99.7%
LP-211
LP-211 is a brain penetrant selective agonist for a 5-HT7 receptor (Ki: 0.58 nM), and >300-fold selectivity over the 5-HT1A receptor.
Rotigotine-
T6647
Rotigotine (N-0923) is a non-ergot dopamine receptor agonist used in the therapy of Parkinson disease and restless leg syndrome. Administered as a once-daily tra...
Haloperidol
T0025
Haloperidol (Serenace) is a highly potent neuroleptic by relieving nervous through the depression of nerve function. In addition, haloperidol has shown about 50-...
PNU-96391
T28435
PNU-96391 (OSU-6162) is an antagonist of dopamine D2 and a partial agonist of 5-HT2A. PNU-96391 can be used in research on the treatment of chronic diseases.
Itopride hydrochloride
T1552
Itopride hydrochloride (Ganaton) is an AChE and D2DR inhibitor.
Flibanserin
T4297
Flibanserin (Girosa) is a serotonergic antidepressant used to treat hypoactive sexual desire disorder. Flibanserin has been associated with a low rate of minor s...
Dopamine hydrochloride
T1644
Dopamine hydrochloride (ASL279) is a naturally occurring catecholamine formed by decarboxylation of dihydroxyphenylalanine and a precursor of norepinephrine and ...
Cariprazine
T4577
Cariprazine (RGH-188) is a novel antipsychotic drug candidate that exhibits high affinity for the D3 (Ki=0.085 nM) and D2 (Ki=0.49 nM) receptors, and moderate af...
Sertindole
T5858
Sertindole (Lu 23-174) is an atypical antipsychotic that binds to dopamine D2 receptors and the serotonin (5-HT) receptor subtypes 5-HT1D, 5-HT2A, and 5-HT2C (Kd...
Promazine hydrochloride
T0766
Promazine hydrochloride (Romtiazin hydrochloride) is a phenothiazine with actions similar to CHLORPROMAZINE but with less antipsychotic activity. It is primarily...
Benserazide hydrochloride
T1517
Benserazide hydrochloride (Ro 4-4602) is a peripherally-acting L-amino acid decarboxylase (AAAD) or DOPA decarboxylase inhibitor.
Domperidone
T0082
Domperidone (R33812)(Motilium) is a dopamine blocker and an antidopaminergic reagent. It blocks the action of. It has strong affinities for the D2 and D3 dopamin...
ABT-724
T7834
ABT-724 is an agonist of dopamine D4 receptor(EC50: 12.4 nM)
Triflupromazine hydrochloride
T0302
Triflupromazine hydrochloride (Fluopromazine hydrochloride), an antipsychotic medication, is Dopamine D1/D2 receptor antagonists.
CyPPA
T20968
CyPPA, a subtype-selective positive modulator of SK channels, decreased spontaneous firing rate, increased the duration of the apamin-sensitive afterhyperpolariz...
ABT 724 trihydrochloride
T22019
ABT 724 trihydrochloride is an effective and selective agonist of the D4 receptor (EC50 = 12.4 nM, 14.3 nM, and 23.2 nM for human, rat and ferret, respectively)....
Quetiapine
T0162
Quetiapine (ICI204636) is used for the therapy of schizophrenia, and for the treatment of acute manic episodes associated with bipolar I disorder. The mechanism ...
Nortriptyline hydrochloride
T1327
Nortriptyline hydrochloride (ELF-101 hydrochloride) is a metabolite of AMITRIPTYLINE that is also used as an antidepressive agent. Nortriptyline is used in major...
Alizapride hydrochloride
T2574
Alizapride hydrochloride (Alizapride HCl) is a dopamine receptor antagonist used for the treatment of nausea and vomiting.
Didesmethyl cariprazine
T15117
Didesmethyl cariprazine, a metabolite of Cariprazine, is the major cyclic active part. Didesmethyl cariprazine has a long half-life of 1-3 weeks. Cariprazine is ...
LP-211
T5387
LP-211 is a brain penetrant selective agonist for a 5-HT7 receptor (Ki: 0.58 nM), and >300-fold selectivity over the 5-HT1A receptor.
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TargetMol