Dehydrogenase

A dehydrogenase (also called DH or DHase in the literature) is an enzyme belonging to the group of oxidoreductases that oxidizes a substrate by reducing an electron acceptor, usually NAD+/NADP+ or a flavin coenzyme such as FAD or FMN. They also catalyze the reverse reaction, for instance alcohol dehydrogenase not only oxidizes ethanol to acetaldehyde in animals but also produces ethanol from acetaldehyde in yeast.

Cat. No.	Product name	CAS No.	Purity
T23209	Qc1	403718-45-6	100%
T23209	Qc1 is an inhibitor of threonine dehydrogenase (TDH) inhibitor and can be used in studies about metabolic diseases.
T72814	11β-HSD1-IN-12	872506-67-7	100%
T72814	11β-HSD1-IN-12 is an 11β-HSD1 inhibitor.11β-HSD1-IN-12 is implicated in the conversion of glucocorticoids in vivo and can be used to study metabolic syndrome and...
T9333	Perfluorooctanoic acid	335-67-1	100%
T9333	Perfluorooctanoic acid (PFOA) (PFOA) is a persistent and widespread industry-made chemical.
T1473	Trilostane	13647-35-3	100%
T1473	Trilostane (Win 24540) is a synthetic derivative of androstane with adrenocortical suppressive properties. Trilostane reversibly inhibits 3 beta-hydroxysteroid d...
T8480	Tenovin-6 Hydrochloride	1011301-29-3	100%
T8480	Tenovin-6 Hydrochloride is an SIRT1, SIRT2 and HDAC8 inhibitor(IC50s of 21 μM, 10 μM, and 67 μM for SirT1, SirT2, and SirT3, respectively), and is also a potent ...
T68664	Epostane	80471-63-2	100%
T68664	Epostane (Win-32729) is a 3β-hydroxysteroid dehydrogenase inhibitor that acts by inhibiting the enzyme 3β-hydroxysteroid dehydrogenase, blocking progesterone pro...
T4515	A939572	1032229-33-6	100%
T4515	A939572 is stearoyl-CoA desaturase1 (SCD1) inhibitor with IC50 values of <4 nM for mSCD1 and 37 nM for hSCD1.
T2346	Enasidenib	1446502-11-9	100%
T2346	Enasidenib (AG-221) is an orally available inhibitor of specific mutant forms of the mitochondrial enzyme isocitrate dehydrogenase type 2 (IDH2), with potential ...
T7741	DS-1001b	1898207-64-1	100%
T7741	DS-1001b is an inhibitor of mutant IDH-1 (Isocitrate Dehydrogenase-1)
T11021	DHODH-IN-12	1263303-93-0	100%
T11021	DHODH-IN-12 is a leflunomide derivative and a weak dihydrorotate dehydrogenase (DHODH) inhibitor with a pKa of 5.07.
T19831	Sodium Oxamate	565-73-1
T19831	Sodium Oxamate (Oxamic acid sodium salt) is an LDH inhibitor that specifically inhibits LDHA. Sodium Oxamate has antitumor activity and induces cell cycle arrest...
T10140	4-Diethylaminobenzaldehyde	120-21-8
T10140	4-Diethylaminobenzaldehyde is a reversible aldehyde dehydrogenase (ALDH) inhibitor (Ki: 4 nM for ALDH1). It displays a potent anti-androgenic effect (IC50: 1.71μ...
T12196	NCT-505	2231079-74-4
T12196	NCT-505 is a potent and selective inhibitor of aldehyde dehydrogenase (ALDH1A1, IC50 = 7 nM) and a weak inhibitor of hALDH1A2, hALDH1A3, hALDH2, hALDH3A1 with IC...
T12438	PfDHODH-IN-1	183945-55-3
T12438	PfDHODH-IN-1 is an analogue of the active Leflunomide metabolite, has antimalarial activity.
TJS1382	Taraxerone	514-07-8
TJS1382	Taraxerone has allelopathic and antifungal effects.Taraxerone prevents catalase, superoxide dismutase, and reduces glutathione concentrations from the decrease i...
T15551	IDH889	1429179-07-6
T15551	IDH889 is a brain penetrant, an allosteric and mutant specific IDH1 inhibitor. IDH889 has effective selectivity for IDH1 R132* mutations (IC50s: 0.02 μM, 0.072 μ...
T14388	AZD 4017	1024033-43-9
T14388	AZD 4017 is an inhibitor of 11β-Hydroxysteroid Dehydrogenase Type 1(11β-HSD1) (IC50: 7 nM).
T4173	R162	64302-87-0	98%
T4173	R162 is an effective glutamate dehydrogenase 1 (GDH1) inhibitor.
T9494	Imidazole-5-propionic acid	1074-59-5	98%
T9494	Imidazole-5-propionic acid (Imidazolylpropionic acid) is a product of histidine metabolism and may involve oxidation or transamination. Imidazole-5-propionic aci...
T10146	4-Hydroxyderricin	55912-03-3	98%
T10146	4-Hydroxyderricin, a potent and selective MAO-B inhibitor (IC50: 3.43 μM), is the main active ingredient of Angelica sinensis, which mildly inhibits dopamine β-h...