T11546 |
HDHODH-IN-1
|
1173715-42-8
|
99.75%
|
|
hDHODH-IN-1 is a human dihydroorotate dehydrogenase (hDHODH) inhibitor with an anti-inflammatory effect.
|
T5702 |
Tenuifoliside B
|
139726-36-6
|
99.69%
|
|
Tenuifoliside B is a natural product from the roots of Polygala tenuifolia.And is a target lactate dehydrogenase inhibitor. Tenuifoliside B has cognitive improv...
|
T5705 |
Glomeratose A
|
202471-84-9
|
99.67%
|
|
Glomeratose A is a lactate dehydrogenase inhibitor.
|
T14501 |
BAY-2402234
|
2225819-06-5
|
99.67%
|
|
BAY-2402234 is an inhibitor of dihydroorotate dehydrogenase (DHODH) for the treatment of myeloid malignancies.BAY 2402234 is a selective low-nanomolar inhibitor ...
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T11022 |
DHODH-IN-13
|
1364791-86-5
|
99.66%
|
|
DHODH-IN-13 is an inhibitor of DHODH with IC50 of 4.3 μM for rat liver. DHODH-IN-13 can be used in studies about rheumatoid arthritis.
|
T22350 |
JX06
|
729-46-4
|
99.66%
|
|
JX06, a potent, selective and covalent PDK inhibitor, inhibits PDK1, PDK2 and PDK3 with IC50 of 49 nM, 101 nM and 313 nM respectively.
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T16068 |
MF-438
|
921605-87-0
|
99.66%
|
|
MF-438 is an effective and orally bioavailable stearoyl-CoA desaturase 1 (SCD1) inhibitor (EC50: 2.3 nM for rSCD1).
|
TQ0042 |
BAY-1436032
|
1803274-65-8
|
99.65%
|
|
BAY-1436032 is a novel, selective and orally available inhibitor of pan-mutant isocitrate dehydrogenase 1 (IDH1).
|
T40168 |
DHODH-IN-16
|
2511248-11-4
|
99.64%
|
|
DHODH-IN-16 is an effective inhibitor of dihydroorotate dehydrogenase (DHODH, IC50 = 0.396 nM for human).
|
T2741 |
Glycyrrhizic acid
|
1405-86-3
|
99.62%
|
|
Glycyrrhizic acid (Glycyrrhizin) is a triterpenoid saponinl with anti-tumor and anti-diabetic activities.
|
T0522 |
Diammonium Glycyrrhizinate
|
79165-06-3
|
99.61%
|
|
Diammonium Glycyrrhizinate (Glycyrrhizin) , an extensively used anti-inflammatory agent, is isolated from the licorice root. It is metabolized to glycyrrhetinic ...
|
T1159 |
Leflunomide
|
75706-12-6
|
99.6%
|
|
Leflunomide (HWA486) is an immunomodulatory agent used in the therapy of rheumatoid arthritis and psoriatic arthritis.
|
T16384 |
Olutasidenib
|
1887014-12-1
|
99.59%
|
|
Olutasidenib (FT-2102) is under the study in the treatment of acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS). Olutasidenib is a highly effective,...
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T1869 |
PluriSIn 1
|
91396-88-2
|
99.59%
|
|
PluriSIn 1 (NSC 14613) is an inhibitor of stearoyl-CoA desaturase (SCD1), the key enzyme in oleic acid biosynthesis, revealing a unique role for lipid metabolism...
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T2601 |
Vidofludimus
|
717824-30-1
|
99.58%
|
|
Vidofludimus (SC12267) (4SC-101, SC12267) is a novel small molecule inhibitor of dihydroorotate dehydrogenase (DHODH).
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T11030 |
DHODH-IN-8
|
1148126-03-7
|
99.57%
|
|
DHODH-IN-8 has antimalarial activity. DHODH-IN-8 is an inhibitor of human and Plasmodium falciparum dihydroorotate dehydrogenase (DHODH) with IC50 of 0.13 μM and...
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T4213 |
NCT-503
|
1916571-90-8
|
99.56%
|
|
NCT-503 is an inhibitor of 3-phosphoglycerate dehydrogenase (PHGDH), inhibiting serine synthesis from 3-phosphoglycerate in cells.
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T11019 |
DHODH-IN-1
|
1800296-63-2
|
99.56%
|
|
DHODH-IN-1 is a potent dihydroorotate dehydrogenase (DHODH) inhibitor with IC50 of 25 nM. DHODH-IN-1 is an inhibitor of the pyrimidine biosynthetic pathway.
|
T67903 |
11β-HSD1 inibitor 17
|
946394-50-9
|
99.56%
|
|
11β-HSD1 inibitor 17 is an inhibitor of 11β-hydroxysteroid dehydrogenase (11β-HSD1).
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T14878 |
CAY10566
|
944808-88-2
|
99.54%
|
|
CAY10566 shows excellent cellular activity in blocking the conversion of saturated long-chain fatty acid-CoAs (LCFA-CoAs) to monounsaturated LCFA-CoAs in HepG2 c...
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