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Cysteine Protease

Cysteine proteases, also known as thiol proteases, are enzymes that degrade proteins. These proteases share a common catalytic mechanism that involves a nucleophilic cysteine thiol in a catalytic triad or dyad.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T1850 Balicatib 354813-19-7 97.78%
Balicatib
Balicatib (AAE581) is a potent and selective inhibitor of cathepsin K, used in trials studying the treatment of osteoporosis.
T6432 Calpeptin 117591-20-5 97.52%
Calpeptin
Calpeptin is a potent, cell-permeable calpain inhibitor.
T3420 CA-074 methyl ester 147859-80-1 97.26%
CA-074 methyl ester
CA-074 methyl ester (Cathepsin B Inhibitor IV) is a specific inhibitor of Cathepsin B with neuroprotective, anti-cancer, and anti-inflammatory effects.
T1080 2-Aminoethanethiol 60-23-1 95.00%
2-Aminoethanethiol
2-Aminoethanethiol (Cysteamine) is a Cystine Depleting Agent. The mechanism of action of cysteamine is as a Cystine Disulfide Reduction.
T0448 (S)-(+)-Ibuprofen 51146-56-6 100%
(S)-(+)-Ibuprofen
(S)-(+)-Ibuprofen (Dexibuprofen) , is a non-steroidal anti-inflammatory drug (NSAID), inhibiting cyclooxygenase (COX).
T2470 MDL-28170 88191-84-8
MDL-28170
MDL-28170 (Calpain Inhibitor III) is a Cysteine protease.
T19503 Papain 9001-73-4
Papain
Papain is a cysteine protease of the peptidase C1 family. Papain is used in food, pharmaceutical, textile, and cosmetic industries.
T6035 Odanacatib 603139-19-1
Odanacatib
Odanacatib is an inhibitor of cathepsin K with potential anti-osteoporotic activity.
T6573 E 64c 76684-89-4
E 64c
E 64c (EP 475) , a derivative of E-64, is an irreversible and membrane-permeant cysteine protease inhibitor.
T13288 VBY-825 1310340-58-9 98%
VBY-825
VBY-825 is a reversible inhibitor of cathepsin with high potency against cathepsins B, L, S and V.
T37753 Aureusimine B 170713-71-0 98%
Aureusimine B
Aureusimine B, also known as phevalin, is a natural pyrazinone produced by certain fungi and by Staphylococcus spp., including S. aureus. Its synthesis appears t...
T3525 PD150606 179528-45-1 98%
PD150606
PD150606 is a selective nonpeptide calpain inhibitor with neuroprotective activity that inhibits μ-calpains and m-calpains. Inhibits erythrocyanine-induced Ca2+ ...
TP2056L Acetyl-Calpastatin (184-210)(human) acetate 98%
Acetyl-Calpastatin (184-210)(human) acetate
Acetyl-Calpastatin (184-210)(human) acetate is a potent, selective and reversible calpain inhibitor with Ki values of 0.2 nM and 6 μM for µ-calpain and cathepsin...
T38469 (Rac)-Z-Phe-Phe-FMK 108005-94-3 98%
(Rac)-Z-Phe-Phe-FMK
(Rac)-Z-Phe-Phe-FMK (Cathepsin L-IN-2) is a cathepsin L inhibitor that inhibits the tendency of β-amyloid to induce apoptotic changes .
Balicatib
T1850
Balicatib (AAE581) is a potent and selective inhibitor of cathepsin K, used in trials studying the treatment of osteoporosis.
Calpeptin
T6432
Calpeptin is a potent, cell-permeable calpain inhibitor.
CA-074 methyl ester
T3420
CA-074 methyl ester (Cathepsin B Inhibitor IV) is a specific inhibitor of Cathepsin B with neuroprotective, anti-cancer, and anti-inflammatory effects.
2-Aminoethanethiol
T1080
2-Aminoethanethiol (Cysteamine) is a Cystine Depleting Agent. The mechanism of action of cysteamine is as a Cystine Disulfide Reduction.
(S)-(+)-Ibuprofen
T0448
(S)-(+)-Ibuprofen (Dexibuprofen) , is a non-steroidal anti-inflammatory drug (NSAID), inhibiting cyclooxygenase (COX).
MDL-28170
T2470
MDL-28170 (Calpain Inhibitor III) is a Cysteine protease.
Papain
T19503
Papain is a cysteine protease of the peptidase C1 family. Papain is used in food, pharmaceutical, textile, and cosmetic industries.
Odanacatib
T6035
Odanacatib is an inhibitor of cathepsin K with potential anti-osteoporotic activity.
E 64c
T6573
E 64c (EP 475) , a derivative of E-64, is an irreversible and membrane-permeant cysteine protease inhibitor.
VBY-825
T13288
VBY-825 is a reversible inhibitor of cathepsin with high potency against cathepsins B, L, S and V.
Aureusimine B
T37753
Aureusimine B, also known as phevalin, is a natural pyrazinone produced by certain fungi and by Staphylococcus spp., including S. aureus. Its synthesis appears t...
PD150606
T3525
PD150606 is a selective nonpeptide calpain inhibitor with neuroprotective activity that inhibits μ-calpains and m-calpains. Inhibits erythrocyanine-induced Ca2+ ...
Acetyl-Calpastatin (184-210)(human) acetate
TP2056L
Acetyl-Calpastatin (184-210)(human) acetate is a potent, selective and reversible calpain inhibitor with Ki values of 0.2 nM and 6 μM for µ-calpain and cathepsin...
(Rac)-Z-Phe-Phe-FMK
T38469
(Rac)-Z-Phe-Phe-FMK (Cathepsin L-IN-2) is a cathepsin L inhibitor that inhibits the tendency of β-amyloid to induce apoptotic changes .
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TargetMol