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(1)
By Target- ALK
- Apoptosis(1)
- PROTACs(1)
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- Apelin receptor
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- cAMP
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- GTPase
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Results for "
target/ALK/2
" in TargetMol Product Catalog- Inhibitors & Agonists1
- PROTAC Products1
PROTAC EML4-ALK Degrader-1
Pro-BA
T211144
PROTACEML4-ALK Degrader-2 (Pro-BA) is a selective and orally active EML4-ALK PROTAC degrader without a linker, demonstrating a DC50 of 74 nM and a T1/2 of 8 hours in H1322 cells. It relies on the GID4 and proteasome pathways to facilitate the ubiquitination of target proteins, leading to apoptosis. PROTACEML4-ALK Degrader-2 is applicable in cancer research.
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