this compound r-enantiomer

(R)-Norfluoxetine is the (R)-enantiomer of Norfluoxetine. It functions as a potent serotonin reuptake inhibitor, with a Ki value of 13 nM. This compound is utilized in the research of depression.

(R)-Acenocoumarol ((R)-Acenocoumarin; (R)-Nicoumalone) is a short-acting, orally administered anticoagulant that works by inhibiting vitamin K epoxide reductase (vitamin K1 recycling), similar to Warfarin. It demonstrates greater anticoagulant potency in vivo compared to Warfarin. This compound has a single chiral center, resulting in two enantiomeric forms. The (R)-enantiomer has a longer plasma elimination half-life of 6.6 hours, slower plasma clearance of 1.9 L/h, and stronger anticoagulation effects than the (S)-enantiomer.

(R)-CDK2 degrader 6 (Compound 7) is the R enantiomer of CDK2 degrader 6. It functions as a selective molecular glue degrader for CDK2, with a DC50 of 27.0 nM within 24 hours. This compound can be utilized in breast cancer research.

(R,R)-Reboxetine mesylate, an antidepressant agent, exhibits high bioavailability and is the (R,R) enantiomer of Reboxetine, a selective noradrenaline reuptake inhibitor. Contrasting its counterpart, the (S,S) enantiomer, this compound demonstrates low affinity for alpha-adrenergic and muscarinic receptors, alongside low toxicity in animals.

RK-0133114, a G9a inhibitor and the R-enantiomer of RK-701, exhibits potent inhibition of G9a with an IC50 value of 3.7 μM. This compound is utilized in research focused on sickle cell disease (SCD) [1].

(R)-(4-NH2)-Exatecan, the R enantiomer of (4-NH2)-Exatecan (Compound A), is a derivative of Exatecan and functions as a topoisomerase inhibitor. This compound is utilized in synthesizing antibody-drug conjugates (ADCs) [1].

(R)-Methyl 3-hydroxybutanoate is an enantiomer where the hydroxyl (-OH) group on the third carbon atom is oriented to the right when viewed from the methyl (-CH3) group. It appears as a colorless and transparent liquid, soluble in organic solvents like ethanol and ether but insoluble in water. This compound is commonly used as a building block in the synthesis of various organic compounds, including pharmaceuticals, agrochemicals, and flavorings. Additionally, it serves as a chiral auxiliary in asymmetric synthesis reactions, which involve the stereoselective formation of chemical bonds.

(+)-15-epi Cloprostenol is a synthetic analogue of prostaglandin F2α (PGF2α) and functions as a potent FP receptor agonist. The compound (+)-15-epi Cloprostenol is the 15(S) or 15β-hydroxy enantiomer of (+)-(+)-15-epi Cloprostenol. Compared to the 15(R)-(+)-15-epi Cloprostenol, this epimer exhibits significantly lower activity as an FP receptor ligand. However, the specific activity of this isomer remains inadequately studied.

(S)-(−)-Docosahexaenyl-1'-hydroxy-2'-propylamide is the enantiomer of (R)-(−)-Docosahexaenyl-1'-hydroxy-2'-propylamide. (R)-(-)-Docosahexaenyl-2'-hydroxy-1'-propylamide is a homolog of dehydroepiandrosterone (DHEA). This compound is characterized by the addition of an (R)-β-methyl group to the terminal ethanolamine carbon atom.