sweetener

Aspartame (SC-18862), an artificial, non-carbohydrate sweetener, is aspartyl-phenylalanine-1-methyl ester.

Acesulfame potassium is a non-nutritive sweetener.

Sucralose is a non-nutritive artificial sweetener and sugar substitute that stimulates appetite in rodents by activating a conserved neural fasting response.

Rebaudioside D is a potential sweetener. Rebaudioside D shows similar stability when exposed to simulate stomach and small intestine fluids, with susceptibility to hydrolytic degradation by enteric bacteria collected from the cecum.

Neotame (HSDB 7965) is a white-colored, dipeptide methyl ester, which is found to be a highly potent and non-nutritive sweetener or flavour enhancer and hence finds applications in a variety of foods.

D-Sorbitol (Sorbitol) is a polyhydric alcohol with about half the sweetness of sucrose, occurring naturally and also produced synthetically from glucose. Formerly used as a diuretic, it may still be used as a laxative and in irrigating solutions for certain surgical procedures. It is also utilized in various manufacturing processes, as a pharmaceutical aid, and in several research applications.

A natural, noncaloric sweetener with a potency 300 times more than that of regular sucrose. Exhibits transepithelial p-aminohippurate transport via organic anion transport system interference.

Saccharin (O-Sulfobenzimide) is a flavoring agent and non-nutritive sweetener.

Xylitol (Ribitol) is a five-carbon sugar alcohol derived from XYLOSE by reduction of the carbonyl group. It is as sweet as sucrose and used as a noncariogenic sweetener.

D-Glucose (Glucopyranose) is a monosaccharide, a natural glucose, a sweetener. D-Glucose is the main functional substance of living organisms, and is used as a nutrient in medicine, with diuretic, detoxification and cardiotonic effects.

Cyclamic acid (NSC-220327) is an artificial sweetening agent, usually employed as Na or Ca salt (cyclamate). Use suspended in some countries, including USA, because of possible weak carcinogenic activity (disputed).

Naringin dihydrochalcone (Naringin DC) is an inhibitor of CYP enzymes, used as an artificial sweetener.

Neohesperidin Dihydrochalcone (Neohesperidin DC) is an artificial sweetener derived from citrus.

Perillartine (DL-Perillartine) is a sweetener. Perillartine activates the taste receptor type 1 member 2 (Tas1r2) subunit in a species-dependent manner.

Isosteviol ((-)-Isosteviol), a common natural sweetener, belongs to tetracyclic diterpene glycosides. The pharmacology researches have suggested that stevioside and its hydrolysis products, steviol, isosteviol and steviolbioside, have many biological activities, such as reducing blood glucose, lowering blood pressure, anti-inflammation, anti-tumor, anti-diarrhea, antibacterium, immunoregulation, etc.

PALATINOSE (TNP-470) is a natural occurring disaccharide composed of alpha-1,6-linked glucose and fructose. PALATINOSE has a beneficial effect on liver metabolic functions and might therefore be a good substitute for sucrose as a sweetener.

Isomaltitol is sugar alcohol. Isomaltitol is commonly used as a sweetener in food products.

Mogroside I E1, a triterpenoid glycoside isolated from the extracts of Luo Han Guo, acts as a nonsugar sweetener.

Saccharin sodium is a nonnutritive artificial sweetener. Saccharin sodium is widely applied in the manufacturing of various food products and pharmaceuticals, offering consistent sweetness without caloric contribution, supporting dietary studies, formulation development, and industrial applications in food and pharmaceutical sciences.

Hesperidin dihydrochalcone, a non-toxic sweetener with high sweetness and low calories, exhibits multiple biological activities including anti-oxidation, liver and kidney protection, bacteriostasis, and enhancement of gastrointestinal health.

Alitame is a high-intensity sweetener and sugar substitute widely used in biochemical experiments and drug synthesis research.

Abrusoside D is a triterpenoid saponin found in Abrus precatorius and can be used as a sweetener.

Advantame anhydrous is a non-caloric sweetener, synthesized from isovanillin and aspartame. The U.S. Food and Drug Administration has approved Advantame for general use in foods and beverages except for meat and poultry as a food additive.

Mogroside V is a widely used sweetener, has in vitro AMPK activating effect, it also has anti-inflammatory potential in murine macrophages and a murine ear edema model, and has the potential to protect against LPS-induced airway inflammation in a model of ALI. Mogroside V has antioxidant properties and possesses tumor growth inhibitory activity in pancreatic cancer models.