salidroside

Salidroside is a bioactive phenolic glycoside compound isolated from Rhodiola rosea and is a prolyl endopeptidase inhibitor. Salidroside can alleviate cachexia symptoms in a tumor cachexia mouse model by activating mTOR signaling and protect dopaminergic neurons by enhancing PINK1/Parkin-mediated mitochondrial autophagy. Salidroside can also inhibit the growth of cancer cells by regulating the CDK4-cyclin D1 pathway to block the G1 phase and/or regulating the Cdc2-cyclin B1 pathway to block the G2 phase.

Salidroside (Standard) is a reference standard for research and analysis in studies involving Salidroside. Salidroside is a bioactive phenolic glycoside compound isolated from Rhodiola rosea and is a prolyl endopeptidase inhibitor. Salidroside can alleviate cachexia symptoms in a tumor cachexia mouse model by activating mTOR signaling and protect dopaminergic neurons by enhancing PINK1/Parkin-mediated mitochondrial autophagy. Salidroside can also inhibit the growth of cancer cells by regulating the CDK4-cyclin D1 pathway to block the G1 phase and/or regulating the Cdc2-cyclin B1 pathway to block the G2 phase.

Salidroside-3-O-glucopyranoside is an anti-inflammatory natural product exhibiting inhibitory activity against TNF (IC50=38.18 mg/L).

6'-O-Galloylsalidroside has antiviral activity and inhibits HIV.

3-Hydroxysalidroside-4-O-glucopyranoside is a natural product that can be used in related research in the field of life sciences. Its product number is TN8821.

Angiogenesis Agent 1 (Compound C-31), a glycoside analogue derived from salidroside, acts as an activator of the HIF-1α pathway and shows potential in diabetic hind limb ischemia research [1].

Nigerose, a disaccharide identified in Acremonium, effectively maintains stability in HL-60 cells post-cryopreservation by preventing elevations in malondialdehyde (MDA) and reactive oxygen species (ROS) levels, and inhibiting lactate dehydrogenase (LDH) release, when administered at a 150 µM concentration alongside the glycoside salidroside.