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Results for "
ro 31 8220
" in TargetMol Product Catalog- Inhibitors & Agonists2
ro 31-8220
T6643L125314-64-9
Ro 31-8220 is a potent inhibitor of PKC with IC50 values of 5, 24, 14, 27, 24, and 23 nM for PKCα, PKCβI, PKCβII, PKCγ, PKCε, and rat brain PKC, respectively. Ro 31-8220 also significantly inhibits MAPKAP-K1b, MSK1, S6K1, and GSK3β with IC50 values of 3, 8, 15, and 38 nM, respectively, without affecting MKK3, MKK4, MKK6, and MKK7.
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Ro 31-8220 Mesylate
Cited
Ro 31-8220 methanesulfonate, Bisindolylmaleimide IX mesylate
T6643138489-18-6
Ro 31-8220 Mesylate (Bisindolylmaleimide IX mesylate) is a pan-PKC inhibitor for PKC-α βI βII γ ε (IC50: 5 24 14 27 24 nM), and also shows potent inhibition against MSK1, MAPKAP-K1b, S6K1, and GSK3β.
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