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Results for "
fmoc-peg2-val-cit-pab-oh
" in TargetMol Product Catalog- Inhibitors & Agonists1
- Cell Research1
Fmoc-PEG2-Val-Cit-PAB-OH
TYD-019452055024-59-2
Fmoc-PEG2-Val-Cit-PAB-OH is a cleavable ADC linker that features a Boc-protected amine, hydrophilic PEG spacer, and a Val-Cit-PAB dipeptide. The benzyl alcohol on the PAB can be used for conjugating reactive groups (e.g., PNP) to attach a payload. The Fmoc protecting group is removable with piperidine, revealing a primary amine for amide bond formation in conjugation reactions. The Val-Cit-PAB segment is cleaved by cellular proteases to efficiently release the payload inside cells.
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