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By Target- Topoisomerase
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By Target By ResearchField- Cancer(1)
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Results for "
f14512hydrochloride
" in TargetMol Product Catalog.- Inhibitors & Agonists1
F-14512 Hydrochloride
T27299L866874-39-7
F-14512 Hydrochloride is a highly potent and tumor-selective inhibitor of DNA topoisomerase II. F-14512 Hydrochloride enhances topoisomerase II inhibition through the high affinity of polyamines for DNA, enabling selective cellular uptake. It exhibits significant cytotoxicity against tumor cells with high PTS activity and induces DNA damage and apoptosis. F-14512 Hydrochloride has demonstrated potent antitumor activity in various tumor models, including MX-1 breast cancer, HL-60 leukemia, and A2780 ovarian cancer. F-14512 Hydrochloride can be used in cancer treatment research.
- $30
Size
QTY
F14512
T27299866874-63-7In house
F-14512 (free base) is a topoisomerase II inhibitor for the study of acute myeloid leukemia.
- $293
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QTY
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