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Results for "
endosulfan i
" in TargetMol Product Catalog- Inhibitors & Agonists2
Endosulfan I
Endosulfan A, Alpha-Benzoepin
T37665959-98-8
Endosulfan I is one of the two major stereoisomers of the broad-spectrum insecticide Endosulfan, exhibiting inhibitory activity against the GABA benzodiazepine picrotoxin complex (IC50 = 30 nM) and disrupting zebrafish embryonic development.
- $35
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Endosulfan II
β-Endosulfan,Endosulfan B
T8525833213-65-9
Endosulfan II, an organochlorine insecticide and a stereoisomer of Endosulfan I, effectively targets various insects such as bollworms and tobacco budworms, with lethal doses (LD50s) of 4.14 and 4.95 mg/g, respectively. It interacts with GABA receptors in rat brain membranes, demonstrating an inhibition concentration (IC50) of 60 nM. Notably, Endosulfan II exhibits lower toxicity in rats compared to Endosulfan I, with LD50 values of 240 and 18 mg/kg, respectively.
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