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dcn1-ubc12

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    8
    TargetMol | Inhibitors_Agonists
DCN1-UBC12-IN-4
T20162826028-65-9
DCN1-UBC12-IN-4 (compound 5p) acts as an inhibitor of DCN1-UBC12, exhibiting an IC50 value greater than 10000 nM and possesses antitumor activity.
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10-14 weeks
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DCN1-UBC12-IN-1
T636472374827-31-1
DCN1-UBC12-IN-1 is a potent and specific DCN1-UBC12 inhibitor with an IC50 value of 2.86 nM and anti-cardiac fibrogenic activity.
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6-8 weeks
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DCN1-UBC12-IN-2
T638202374827-47-9
DCN1-UBC12-IN-2 is a potent and specific DCN1-UBC12 inhibitor with an IC50 value of 9.55 nM, targeting DCN1-UBC12 interactions and inhibiting Ang II-induced activation of cardiac fibroblasts.
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6-8 weeks
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DI-591
T110332245887-38-9
DI-591 is an effective, high-affinity and cell-permeability inhibitor for DCN1-UBC12 interaction. DI-591 binds to DCN1 and DCN2 with Ki values of 12 and nM and 10.4 nM, respectively, and has no obvious binding to DCN3, DCN4 and DCN5 proteins.
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8-10 weeks
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WS-383 free base
T133482247543-65-1
WS-383 free base is a selective and reversible DCN1-UBC12 interaction inhibitor with an IC50 of 11 nM.
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1-2 weeks
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WS-383
T133492247544-02-9
WS-383 is a selective, potent and reversible DCN1-UBC12 interaction inhibitor(IC50 of 11 nM).
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DI-404
T239892187412-79-7
DI-404 is a high-Affinity Peptidomimetic the DCN1-UBC12 Protein-Protein Interaction inhibitor (Kd= 6.9 nM). DI-404 effectively and selectively inhibits the neddylation of cullin 3 over other cullin members.
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3-6 months
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NAcM-OPT HCl(2089293-61-6 free base)
T91402416146-10-4
NAcM-OPT HCL is an orally bioavailable cullin neddylation 1 (DCN1) inhibitor that targets N-Acetyl-UBE2M (E2 conjugating enzyme, UBC12) interaction with DCN1 with IC50 of 79 nM.
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