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cyp4a11/cyp4f2-in-2

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  • Inhibitors & Agonists
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    TargetMol | Inhibitors_Agonists
CYP4A11/CYP4F2-IN-2
T861512280834-99-1
CYP4A11 CYP4F2-IN-2 (compound 15) serves as an orally administered inhibitor targeting CYP4A11 4F2, exhibiting IC50 values of 120 nM and 220 nM, respectively. This compound effectively suppresses 20-HETE production within the rat kidney and shows promise in mitigating the progression of diabetic nephropathy and autosomal dominant polycystic kidney disease [1].
  • $1,820
10-14 weeks
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TP0472993
T679162126874-77-7
CYP4A11 CYP4F2-IN-2 is a potent and orally active dual inhibitor of cytochrome P450 (CYP) 4A11 and CYP4F2, with IC50 values of 140 nM and 40 nM, respectively. Extractable from liver and kidney, CYP4A11 CYP4F2-IN-2 has the potential to treat kidney diseases.
  • $44
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