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Results for "
ae848/420258922hcl
" in TargetMol Product Catalog- Inhibitors & Agonists1
AE-848/42025892 2HCl
T131873L1
AE-848/42025892 2HCl is a small molecule that selectively induces apoptosis in multiple myeloma (MM) cells while sparing normal peripheral blood mononuclear cells, inhibiting U266 and RPMI8226 cell viability in a dose- and time-dependent manner, AE-848/42025892 2HCl induces the cleavage of caspase-8, caspase-3, and poly ADP-ribose polymerase (PARP), resulting in loss of mitochondrial membrane potential (MMP).thereby providing a therapeutic window for MM treatment.
- $195
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