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By Target- Apoptosis
- Aurora Kinase(1)
- CDK(1)
- DYRK(1)
- FLT(1)
- GSK-3(1)
- NF-κB(1)
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By Target By ResearchField- Nervous System(1)
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Results for "
activation of astrocytes and microglia
" in TargetMol Product Catalog.- Inhibitors & Agonists2
- Recombinant Protein1
NOSH-aspirin
NBS-1120
T2138671357362-67-4
NOSH-aspirin (NBS-1120) is an orally active hybrid molecule that releases nitric oxide and hydrogen sulfide. It inhibits the proliferation of pancreatic cancer cells and induces apoptosis. In a mouse model of pancreatic cancer, NOSH-aspirin suppresses tumor growth and inhibits NF-κB and FoxM1. Additionally, it alleviates motor deficits and dopaminergic neuronal degeneration in a rat model of Parkinson's disease and reduces neuroinflammation caused by the activation of microglia and astrocytes. NOSH-aspirin is useful for research in cancers such as pancreatic cancer and neurological disorders like Parkinson's disease.
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