T7902

Ozenoxacin (T-3912) is a quinolone antibacterial. It shows potent activities against the main microorganisms isolated from soft tissue and skin infections.

ALK2-IN-5, a pyrazolopyrimidine compound, serves as an inhibitor of ALK2 and FGFR, targeting disorders linked with their activity, including cancer [1].

GSK3839919A is a potent allosteric inhibitor of HIV-1 integrase [1].

BACE1-IN-13 (Compound 36), an orally active inhibitor of BACE1, exhibits high potency with an IC50 of 2.9 nM and demonstrates greater efficacy in hAβ42 cells (IC50 = 1.3 nM). It is considered safe for the cardiovascular system and induces a sustained reduction of Aβ42 in both mouse and dog animal models [1].

CaSR Antagonist-1 is a potent inhibitor of the calcium-sensing receptor (CaSR) with an inhibitory concentration (IC50) of 50 nM, suitable for the investigation of diseases related to dysregulated bone or mineral homeostasis, including osteoporosis [1].

Androgen receptor-IN-5 is a potent inhibitor of the androgen receptor with anticancer properties. It additionally suppresses the synthesis of IL-17A, IL-17F, and INF-γ.

TNF-α-IN-10 (compound 8a) is an inhibitor of IL-6 and TNF-α, exhibiting anti-inflammatory activity [1].

Tankyrase-IN-5 (Compound 30f), structurally related to MSC2504877, effectively inhibits tankyrase isoforms TNKS1 and TNKS2 with IC50 values of 2.3 nM and 7.9 nM, respectively [1].

A1/A3 AR Antagonist 3 is a dual A1R/A3R antagonist that demonstrates high affinity within the low-micromolar to nanomolar range, and is potentially useful in the research of chronic heart diseases [1].

Compound 135, also known as p38 Kinase Inhibitor 4, is a potent inhibitor of p38 [1].

IpOHA is a potent inhibitor of plant KARI and functions as an antimycobacterial agent, demonstrating a K_i value of 97.7 nM against Mycobacterium tuberculosis (Mt) [1].

Ozenoxacin-D3 is a deuterated compound of Ozenoxacin. Ozenoxacin (T7902) has a CAS number of 245765-41-7. Ozenoxacin (T7902) is a novel quinolone-class antibiotic that exhibits activity against the majority of microorganisms isolated from skin and soft tissue infections.