T1977

Dorsomorphin (BML-275) is an AMPK inhibitor (Ki=109 nM) that is selective and ATP-competitive. Dorsomorphin inhibits the BMP type I receptors ALK2, ALK3, and ALK6. Dorsomorphin induces autophagy, and possesses antitumor activity.

Methylisothiazolinone (MI) is a powerful synthetic biocide and preservative within the group of isothiazolinones.

Trilaurin (Glyceryl tridodecanoate) is a triacylglycerol found in dietary fats. Trilaurin can be used in cosmetic products as a thickening agent.

Equilenin (E 400), a natural estrogen, is a specific fluorescent probe for steroid-protein interactions in sex steroid-binding proteins and has a high binding affinity for sex steroid-binding proteins (SBPs) Equilenin is an endocrine disruptor and can be used in the study of breast cancer.

ODQ is an effective and selective soluble guanylyl cyclase (sGC) inhibitor.

2-ATHBI is a S1P lyase inhibitor.

SL-01 is an oral derivative of gemcitabine. SL-01 inhibited human breast cancer growth through the induction of apoptosis. SL-01 inhibited human cancer growth more potently than gemcitabine.