T1446

Bambuterol hydrochloride (KWD-2183 hydrochloride) , a long-acting beta-adrenoceptor agonist, is utilized for the treating of asthma.

ZSET1446 (ST-101) is a T-type calcium channel activator potentially for the treatment of learning deficits in various types of Alzheimer disease (AD) models.

Azido-PEG5-CH2CO2-PFP is a polyethylene glycol (PEG) and Alkyl/ether-based linker compound, essential for synthesizing proteolysis-targeting chimeras (PROTACs), which are used for targeted protein degradation[1].

Azido-PEG5-CH2CO2H is a cleavable 5-unit PEG ADC linker utilized in the synthesis of antibody-drug conjugates (ADCs)[1].

Azido-PEG5-NHS ester is a PEG-based linker for PROTACs that joins two essential ligands, crucial for the formation of PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Azido-PEG5-PFP ester is a Polyethylene Glycol (PEG) and Alkyl/ether-based Proteolysis Targeting Chimera (PROTAC) linker, commonly used for PROTAC synthesis [1].

Azido-PEG5-succinimidyl carbonate is a polyethylene glycol (PEG) derivative featuring a succinimidyl carbonate and an azido group, utilized as a PEG-based PROTAC linker in the synthesis of PROTACs[1].

Azido-PEG6-acid is a PEG-based linker for PROTACs [Proteolysis Targeting Chimeras] that connects two essential ligands, crucial for the formation of PROTAC molecules, enabling selective protein degradation through the ubiquitin-proteasome system within cells.

Azido-PEG6-alcohol is a polyethylene glycol (PEG)-based PROTAC linker utilized in PROTAC synthesis[1]. It also functions as a non-cleavable PEG linker consisting of six units, specifically employed in the synthesis of antibody-drug conjugates (ADCs)[2].

Azido-PEG6-amine is a polyethylene glycol (PEG)-based linker compound commonly employed in the synthesis of Proteolysis Targeting Chimeras (PROTACs)[1]. Additionally, it serves as a non-cleavable 6-unit PEG linker in the synthesis of antibody-drug conjugates (ADCs)[2].

Azido-PEG6-C1-Boc is a PEG-based linker for PROTACs that joins two essential ligands crucial for forming PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Azido-PEG6-C2-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.