T1160

Fusidic acid (Fusidine) is an antibiotic isolated from the fermentation broth of Fusidium coccineum.

IBR2 (Isoquinoline) is a potent and specific RAD51 inhibitor known for its ability to suppress RAD51-mediated DNA double-strand break repair. By interfering with RAD51 multimerization, accelerating proteasome-mediated RAD51 protein degradation, inhibiting cancer cell growth, and inducing apoptosis, IBR2 has proved to be an effective compound in these aspects.

Ibrutinib-D5 is a deuterium-labeled Ibrutinib. Ibrutinib (T1835) is an irreversible Btk inhibitor.

Ibrutinib dimer is an impurity of Ibrutinib. IIbrutinib dimer is a Dimer of Ibrutinib. Ibrutinib is an irreversible Btk inhibitor (IC50: 0.5 nM).

Ibrutinib-MPEA is ibrutinib derivative. Ibrutinib is a covalent and irreversible BTK inhibitor that has been used to treat hematological malignancies.

Ibuprofen-D3 is a deuterium labeled Ibuprofen. Ibuprofen (T1394) is a COX-1 and COX-2 inhibitor (IC50s: 13 μM and 370 μM).

(-)-Ibuprofenamide, an amide prodrug of Ibuprofen, exhibits anti-inflammatory activity.

ICA-105665 (PF-04895162) is a potent and orally active opener of neuronal Kv7.2/7.3 and Kv7.3/7.5 potassium channels. ICA-105665 had low cytotoxic potential in human hepatocytes but inhibited liver mitochondrial function and bile salt export protein (BSEP) transport (IC50 of 311 μM). ICA-105665 can penetrate the central nervous system (CNS) and has antiseizure effects [1][2][3][4].

ICI 118,551 hydrochloride (ICI 118551 hydrochloride) is a highly selective β2 adrenergic receptor antagonist (Kis: 0.7, 49.5, and 611 nM for β2, β1, and β3 receptors).

Epanolol is a potent β-adrenoceptor partial agonist with a greater affinity for β1- than β2-adrenoceptors.

ICI 153110 is an orally active phosphodiesterase inhibitor with both inotropic and vasodilating properties, designed for the treatment of congestive cardiac failure.

Fusidic acid-D6 is the deuterated form of Fusidic acid. Fusidic acid (T1160) (Fusidate) is a steroidal antibacterial antibiotic derived from Fusidium coccineum, lacking corticosteroid effects. It inhibits bacterial growth by preventing the ribosome from releasing elongation factor G (EF-G) during protein synthesis.