T0968

Paclitaxel (Taxol) is a natural product and a microtubule polymer stabilizer. Paclitaxel has anti-tumor activity and causes cell death by inducing mitotic arrest, apoptosis, and cell autophagy.

Paclitaxel-D5 is the deuterated analog of Paclitaxel (TMSM-3141), a diterpenoid natural product originally isolated from Pacific yew bark. Paclitaxel-D5 maintains the parent compound’s ability to stabilize microtubules and induce mitotic arrest leading to apoptosis, and it is widely used as an internal standard in analytical assays and mechanistic drug studies.

Paclitaxel-D5 (benzoyloxy) is the deuterated form of Paclitaxel, a natural antineoplastic agent that stabilizes the polymerization of tubulin. It induces mitotic arrest and apoptosis, ultimately leading to cell death. Additionally, Paclitaxel (T0968) can also induce autophagy.

Paclitaxel-13C is a compound with the C13-labeled isotope of Paclitaxel (TMSM-3141).