10
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T0687 | Simvastatin | MK-0733,MK 733 | Apoptosis , Mitophagy , Ferroptosis , HMG-CoA Reductase , Autophagy |
Simvastatin (MK 733) is an HMG-CoA reductase inhibitor (Ki=0.2 nM) with oral activity. Simvastatin has hypolipidemic activity, inhibits hepatic production of cholesterol, and is also used for the prevention of cardiovasc... | |||
T10324 | Anhydrosimvastatin | Dehydro simvastatin | HMG-CoA Reductase |
Anhydrosimvastatin (Dehydro simvastatin) is an impurity of Simvastatin. Simvastatin is an HMG-CoA reductase inhibitor. | |||
T24865 | Tenivastatin | L-654969,L654969,Simvastatin acid,L 654969,Simvastatin hydroxy acid | ROS , HMG-CoA Reductase |
Tenivastatin (Simvastatin acid) is an anti-hyperlipidemic HMG-CoA reductase inhibitor that inhibits the production of reactive oxygen species (ROS) and can be used in the study of primary hyperlipidemia. | |||
T40557 | Simvastatin Acyl-β-D-glucuronide | ||
Simvastatin Acyl-β-D-glucuronide, a metabolite formed from Simvastatin, acts as a competitive inhibitor of HMG-CoA reductase, showcasing a potent Ki of 0.2 nM. | |||
T10070 | 2'-Ethyl Simvastatin | HMG-CoA Reductase | |
2'-Ethyl Simvastatin is a Mevinolin analog with HMG-CoA reductase inhibition. | |||
T16885 | Simvastatin acid ammonium | Tenivastatin ammonium | Others |
Simvastatin ammonium is an active metabolite of simvastatin lactone mediated. Simvastatin ammonium reduces indoxyl sulfate-mediated reactive oxygen species and modulates OATP3A1 expression in cardiomyocytes and HEK293 ce... | |||
T64292 | Simvastatin acid calcium hydrate | ||
Simvastatin acid (Tenivastatin) calcium hydrate is an orally active inhibitor of HMG-CoA reductase (HMGCR). Simvastatin acid calcium hydrate also inhibits indoxyl sulfate mediated reactive oxygen species (ROS) production... | |||
T72155 | (Rac)-3′-Hydroxy simvastatin | ||
(Rac)-3′-Hydroxy Simvastatin, a metabolite of Simvastatin, acts as a competitive inhibitor of HMG-CoA reductase, demonstrating a K i value of 0.2 nM. | |||
T10136 | 4-Acetylsimvastatin | Others | |
4-Acetylsimvastatin is acetylated simvastatin. Simvastatin is a competitive inhibitor of HMG-CoA reductase (Ki: 0.2 nM). | |||
T20937 | Dodecenylsuccinic anhydride | Rikacid DDSA,Dodecenylsuccinic acid anhydride,DDSA | Others |
Dodecenylsuccinic anhydride (DDSA) can be grafted with collagen hydrogels as a hydrophobic wound dressing to incorporate simvastatin, which has potential application in the treatment of ulcers and prevention of wound inf... |