mpc — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T38707	MPC-0767
	MPC-0767, a potent, selective, and orally active hsp90 inhibitor, is the L-alanine ester prodrug of MPC-3100, exhibiting enhanced chemical stability.
T13298	Verubulin hydrochloride	MPC-6827 hydrochloride	Microtubule Associated
	Verubulin hydrochloride (MPC-6827 hydrochloride) is an agent of blood brain barrier permeable microtubule-disrupting, with potent and broad-spectrum cytotoxic activities,with potent anticancer activity in human MX-1 brea...		Microtubule Associated
T21600	MPC-3100
	MPC-3100 is an orally bioavailable, synthetic, second-generation small-molecule inhibitor of Hsp90 with significant antitumor activity [1].
T17229	Verubulin	MPC 6827	Microtubule Associated
	Verubulin is a microtubule-disrupting agent with potent and broad-spectrum in vitro and in vivo cytotoxic activities.		Microtubule Associated
T5376	Aranidipine	MPC1304	Calcium Channel
	Aranidipine (MPC1304) (MPC1304) is a calcium channel antagonist with potent and long-lasting antihypertensive effects.		Calcium Channel
T5843	Tarenflurbil	MPC7869,(R)-Flurbiprofen,R-flurbiprofen	Retinoid Receptor , Autophagy
	Tarenflurbil ((R)-Flurbiprofen) is the non-cyclooxygenase inhibiting R-enantiomer of the non-steroidal anti-inflammatory drug flurbiprofen, which was assessed as a remedy for Alzheimer's disease.		Retinoid Receptor , Autophagy
T1768	7ACC2		Mitochondrial Metabolism , Monocarboxylate transporter
	7ACC2 is a new potent MCT inhibitor with IC50 of 11 nM for [14C]-lactate influx; new antitumor treatment targeting lactate transport in Y cells.		Mitochondrial Metabolism , Monocarboxylate transporter
T2607	MSDC 0160	CAY10415,Mitoglitazone,MSDC0160,MSDC-0160	Others , IGF-1R , Mitochondrial Metabolism
	MSDC 0160 (CAY10415) is a prototype mTOT-modulating insulin sensitizer being used in trials studying the treatment of Type 2 Diabetes and Alzheimer's Disease.		Others , IGF-1R , Mitochondrial Metabolism
T9235	GW604714X	2,4-Thiazolidinedione, 5-[[5-[6-(4-acetyl-1-piperazinyl)-3-nitro-2-pyridinyl]-2-fluorophenyl]methylene]-	Mitochondrial Metabolism
	GW604714X (2,4-Thiazolidinedione, 5-[[5-[6-(4-acetyl-1-piperazinyl)-3-nitro-2-pyridinyl]-2-fluorophenyl]methylene]-) were found to be potent inhibitors of mitochondrial respiration supported by pyruvate		Mitochondrial Metabolism
T71538	AMPCP
	AMPCP is an Ecto-5'-nucleotidase (CD73) inhibitor.
T74285	EDMPC
	EDMPC, a cationic lipid, exhibits an enhanced capability for DNA delivery to pulmonary tissues. It facilitates intralobar DNA transfer in rodents [1].
T79693	PIMPC		GSK-3
	PIMPC, a compound endowed with antioxidant and metal-chelating properties, acts as a novel inhibitor of glycogen synthase kinase 3 (GSK-3), and exhibits potential therapeutic effects for Alzheimer's disease [1].		GSK-3
T39792	AMPC
	AMPC, a powerful and efficient inhibitor of TFF3, demonstrates inhibitory effects on cell proliferation, survival, oncogenicity, and CSC-like behavior in TFF3-positive CMS4 CRC cells. It acts as a promising standalone an...
T60419	Cyclic HPMPC
	Cyclic HPMPC is a potent antiviral agent that enhances arterial oxygen saturation in mice infected with the lethal vaccinia virus (IHD strain) and alleviates congenital guinea pig cytomegalovirus (GPCMV) infection outcom...
T24495	MPCI
	MPCI is a selective melanocortin-4 receptor antagonist.
T4441	UK-5099	UK 5099,PF-1005023,UK5099	Others , Mitochondrial Metabolism
	UK-5099 (PF-1005023) is a specific and potent inhibitor of MPC carrier activity [1]. It potently inhibits pyruvate-dependent oxygen consumption by rat heart mitochondria (IC50: 50 nM) [1].		Others , Mitochondrial Metabolism
T38715	MSDC-0602K	MSDC-0602K,Azemiglitazone potassium	PPAR
	MSDC-0602K (Azemiglitazone potassium) (Azemiglitazone potassium) is a PPARγ-sparing thiazolidinedione (Ps-TZD) compound that binds to PPARγ with an IC50 of 18.25 μM. It also modulates the mitochondrial pyruvate carrier (...		PPAR
T4639	Azemiglitazone	MSDC 0602	Mitochondrial Metabolism , mTOR
	Azemiglitazone (MSDC 0602) is an insulin sensitizer potentially for the treatment of diabetes.		Mitochondrial Metabolism , mTOR

Compounds

MPC-0767

T38707

Synonym:

Target:

Verubulin hydrochloride

T13298

Synonym: MPC-6827 hydrochloride

Target: Microtubule Associated

Target: Microtubule Associated

Aranidipine

T5376

Synonym: MPC1304

Target: Calcium Channel

Tarenflurbil

T5843

Synonym: MPC7869,(R)-Flurbiprofen,R-flurbiprofen

Target: Retinoid Receptor, Autophagy

7ACC2

T1768

Synonym:

Target: Mitochondrial Metabolism, Monocarboxylate transporter

MSDC 0160

T2607

Synonym: CAY10415,Mitoglitazone,MSDC0160,MSDC-0160

Target: Others, IGF-1R, Mitochondrial Metabolism

GW604714X

T9235

Synonym: 2,4-Thiazolidinedione, 5-[[5-[6-(4-acetyl-1-piperazinyl)-3-nitro-2-pyridinyl]-2-fluorophenyl]methylene]-

Target: Mitochondrial Metabolism

Synonym: UK 5099,PF-1005023,UK5099

Target: Others, Mitochondrial Metabolism

MSDC-0602K

T38715

Synonym: MSDC-0602K,Azemiglitazone potassium

Target: Mitochondrial Metabolism, mTOR

Cat No.	Product Name	Synonyms	Targets
T5782	Bevirimat	YK FH312,MPC-4326,PA-457	HIV Protease
	Bevirimat (PA-457) is a first-in-class inhibitor of HIV-1 maturation, blocking the cleavage of the Gag capsid (CA) precursor, CA-SPI, to mature CA protein during virion maturation.

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPH-00695	OmpC Protein, E. coli, Recombinant (His)	E. coli	E. coli
	Forms pores that allow passive diffusion of small molecules across the outer membrane.; (Microbial infection) Supports colicin E5 entry in the absence of its major receptor OmpF.; (Microbial infection) A mixed OmpC-OmpF ...
TMPH-00696	OmpC Protein, E. coli, Recombinant	E. coli	E. coli
	Forms pores that allow passive diffusion of small molecules across the outer membrane.; (Microbial infection) Supports colicin E5 entry in the absence of its major receptor OmpF.; (Microbial infection) A mixed OmpC-OmpF ...
TMPH-00676	OmpC Protein, E. coli O157:H7, Recombinant (His & Myc & SUMO)	E. coli	E. coli
	Forms pores that allow passive diffusion of small molecules across the outer membrane.
TMPH-02376	OmpC Protein, Klebsiella pneumoniae, Recombinant (His & Myc)	Klebsiella pneumoniae	E. coli
	Forms pores that allow passive diffusion of small molecules across the outer membrane. In K.pneumoniae it has been shown to bind the C1Q component and activate the classical pathway of the complement system.